How does this medication work? What will it do for me?

Nedocromil eye drops belong to a family of medications called mast cell stabililizers. When exposed to something that we are allergic to, mast cells release chemicals that cause the allergic symptoms that we experience. By preventing the release of these chemicals from the mast cells, nedocromil eye drops can help to relieve the eye symptoms associated with allergies, also known as allergic conjunctivitis.

Your doctor may have suggested this medication for conditions other than the ones listed in these drug information articles. As well, some forms of this medication may not be used for all of the conditions discussed here. If you have not discussed this with your doctor or are not sure why you are being given this medication, speak to your doctor. Do not stop using this medication without consulting your doctor.

Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to use this medication if their doctor has not prescribed it.

What form(s) does this medication come in?

Each mL of sterile, aqueous, isotonic, preserved, stabilized, clear pale yellow ophthalmic solution contains nedocromil sodium 2% w/v. Nonmedicinal ingredients: benzalkonium chloride, disodium edetate (EDTA), purified water, and sodium chloride.

How should I use this medication?

The usual recommended dose for adults and children 3 years of age and older is 1 drop in each eye twice a day at regular intervals. Start this medication as closely as possible to the start of your symptoms. To maintain symptom control, use the eye drops on a regular basis throughout your allergy season.

Avoid touching the tip of the dropper to any surface, including the eye. Wash your hands thoroughly before and after using the drops. To instill the drops, tilt your head back and gently pull your lower lid down. Then carefully squeeze out 1 drop into each eye while looking up toward your forehead. Close your eyes gently for a few moments. If you are not sure how to use the drops, talk to your doctor or pharmacist.

Do not wear soft contact lenses during treatment. If you wear hard or gas permeable contact lenses, remove them before using the eye drops, and wait at least 5 minutes before putting your contact lenses back in.

Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a different dose than the ones listed here, do not change the way that you are using the medication without consulting your doctor.

It is important to use this medication exactly as prescribed by your doctor. If you miss a dose, instill it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not instill a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.

Store this medication at room temperature, protect it from direct sunlight, and keep it out of the reach of children.

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.

Who should NOT take this medication?

Do not use nedocromil eye drops if you are allergic to nedocromil or any ingredients of the medication.

What side effects are possible with this medication?

Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.

The side effects listed below are not experienced by everyone who uses this medication. If you are concerned about side effects, discuss the risks and benefits of this medication with your doctor.

The following side effects have been reported by at least 1% of people using this medication. Many of these side effects can be managed, and some may go away on their own over time.

Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.

  • blurred vision
  • burning, stinging, watery, or irritated eyes after using the eye drops
  • eye redness
  • headache
  • sensitivity of eyes to light
  • sore eyes
  • sore throat
  • taste changes

Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking this medication.

Are there any other precautions or warnings for this medication?

Before you begin using a medication, be sure to inform your doctor of any medical conditions or allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use this medication.

Contact lenses: Do not wear soft contact lenses while you are using this medication. Benzalkonium chloride, one of the preservatives in this medication, can accumulate on soft contact lenses and possibly irritate the cornea of the eye. If you wear hard or gas permeable contact lenses, remove them before using this medication, and insert them again at least 5 minutes after using the eye drops.

Pregnancy: This medication should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while using this medication, contact your doctor immediately.

Breast-feeding: It is not known if nedocromil passes into breast milk. If you are a breast-feeding mother and are taking this medication, it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.

Children: The safety and effectiveness of using this medication have not been established for children under 3 years of age.

What other drugs could interact with this medication?

Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications that you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them. Depending on your specific circumstances, your doctor may want you to:

  • stop taking one of the medications,
  • change one of the medications to another,
  • change how you are taking one or both of the medications, or
  • leave everything as is.

An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.