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Drug Info > S > Salazopyrin
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DIN (Drug Identification Number)


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Brand Name

Salazopyrin

Common Name
sulfasalazine


In this drug factsheet:



DIN (Drug Identification Number)

02064472 SALAZOPYRIN 500MG EN-TABLET
02064480 SALAZOPYRIN 500MG TABLET

How does this medication work? What will it do for me?

Sulfasalazine belongs to the class of medications called anti-inflammatories. It is used to treat inflammatory bowel disease such as ulcerative colitis, proctitis or distal ulcerative colitis, and Crohn's disease. It helps control symptoms by reducing chronic inflammation in the bowel. The enteric-coated tablets can be used to treat rheumatoid arthritis when treatment with other medications has not helped. It may take 1 to 2 months before you see any results.

This medication may be available under multiple brand names and/or in several different forms. Any specific brand name of this medication may not be available in all of the forms or approved for all of the conditions discussed here. As well, some forms of this medication may not be used for all of the conditions discussed here.

Your doctor may have suggested this medication for conditions other than those listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are taking this medication, speak to your doctor. Do not stop taking this medication without consulting your doctor.

Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take this medication if their doctor has not prescribed it.

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How should I use this medication?

The dose of sulfasalazine varies widely according to the condition being treated and the needs of the person. The dose is usually started at a low dose and increased to the dose that is most effective. Side effects are more likely to occur with total daily doses of 4 g (4,000 mg) daily or more. Doses of sulfasalazine should be taken at regular and even intervals over the 24 hour daily period. If you are taking sulfasalazine for an intestinal inflammatory disease, the night-time dose interval should not be longer than eight hours. Doses for children are calculated on the basis of body weight.

The uncoated tablets should be taken with a meal if possible. The enteric-coated tablets must not be chewed or crushed; they should be swallowed whole.

While taking sulfasalazine, drink an adequate amount of fluids to minimize the risk of crystals in the urine and the forming of kidney stones.

Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones given here, do not change the way that you are taking the medication without consulting your doctor.

It is important that this medication be taken exactly as prescribed by your doctor. If you miss a dose, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.

Store this medication at room temperature, protect it from light and moisture, and keep it out of the reach of children.

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.





What form(s) does this medication come in?

Tablets
Each yellow-orange, round, convex tablet, engraved with "KPh" on one side with "101" and a score on the other side, contains sulfasalazine 500 mg. Nonmedicinal ingredients: silicon dioxide, starch, and magnesium stearate. This medication does not contain tartrazine.

EN-tabs
Each yellow-orange, elliptical, convex, enteric-coated tablet, engraved with "KPh" on one side and "102" on the other side, contains sulfasalazine 500 mg. Nonmedicinal ingredients: beeswax, carnauba wax, cellulose acetate phthalate, glyceryl monostearate, polyethylene glycol, propylene glycol, and talc. This medication does not contain tartrazine.

Who should NOT take this medication?

Do not take sulfasalazine if you:

  • are allergic to sulfasalazine or any ingredients of the medication
  • are allergic to sulfonamides or salicylates (e.g., ASA or aspirin)
  • have a liver condition called porphyria as this type of medication has been reported to bring on an attack
  • have had acute asthmatic attacks, hives, rhinitis, or other allergic symptoms that are brought on by ASA or other nonsteroidal anti-inflammatory drugs (NSAIDs; e.g., ibuprofen, naproxen)
  • have an intestinal or urinary blockage
  • have severely decreased kidney function

Do not give this medication to children under 2 years of age.



 

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