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Drug Info > F > Fraxiparine
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In this drug factsheet:

DIN (Drug Identification Number)


How does this medication work? What will it do for me?

Nadroparin belongs to the class of medications known as anticoagulants or antithrombotic agents. These medications reduce the clotting ability of the blood and can reduce the risk of harmful blood clots forming in blood vessels.

Nadroparin is used to prevent and treat deep vein thrombosis (DVT). This condition leads to the formation of blood clots in the blood vessels in the leg. These blood clots can sometimes travel to the lungs and block blood vessels there, resulting in a serious condition known as pulmonary embolism.

Nadroparin is used to prevent DVT and pulmonary embolism in people who are undergoing general surgery or orthopaedic surgery (e.g., hip or knee replacement). It is also used to prevent clotting in people undergoing hemodialysis. Nadroparin is also used to treat unstable angina and heart attack survivors.

Your doctor may have suggested this medication for conditions other than those listed in these drug information articles. As well, some forms of this medication may not be used for all of the conditions discussed here. If you have not discussed this with your doctor or are not sure why you are being given this medication, speak to your doctor. Do not stop using this medication without consulting your doctor.

Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to use this medication if their doctor has not prescribed it.

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How should I use this medication?

The recommended dose depends on the individual and the condition being treated. Nadroparin is injected under the skin (subcutaneously). Your doctor will recommend the dose that is most likely to prevent blood clots yet not cause you to bleed easily. Your doctor or health care professional will show you how to inject the medication yourself. If you have any questions about how to use the medication, contact your doctor.

Steps to use the medication:

  1. Before injecting nadroparin, wash your hands and the area of skin you will inject. Only use the injection if the solution appears clear and particle-free.
  2. Lie down and gently pinch a fold of skin (usually in the lower abdomen) between your finger and thumb. Choose alternate places on the lower abdomen for each injection (e.g., right side one day, left side the next day).
  3. Push the entire needle vertically into the skin and then press down on the syringe plunger to inject the medication. Make sure you are holding the skin the entire time you are injecting the needle and pressing down on the syringe plunger.
  4. After giving the injection, remove the needle from the skin. Use the safety shield to prevent the needle from injuring others.
  5. Use an alcohol swab to apply light pressure to the injection area for several seconds. Do not rub the site afterwards.
  6. Dispose of the syringe and needle safely (using a sharps container). Each syringe is for a single use only.

Many things can affect the dose of a medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are using the medication without consulting your doctor.

It is important to use this medication exactly as prescribed by your doctor. If you miss a dose, contact your doctor or pharmacist. Do not inject a double dose to make up for a missed one.

Store this medication at room temperature and keep it out of the reach of children. Do not refrigerate or freeze the medication.

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.

What form(s) does this medication come in?

Fraxiparine® Prefilled Syringes
Each mL of aqueous solution contains nadroparin calcium 9,500 anti-Xa IU. Single dose, disposable prefilled glass syringes of 0.3 mL (ungraduated green syringes), 2,850 anti-Xa IU; 0.4 mL (ungraduated orange syringes), 3,800 anti-Xa IU; 0.6 mL (graduated brown syringes), 5,700 anti-Xa IU; 0.8 mL (graduated green [teal] syringes), 7,600 anti-Xa IU; and 1 mL (graduated violet syringes), 9,500 anti-Xa IU.

Fraxiparine Forte® Prefilled Syringes
Each mL of aqueous solution contains nadroparin calcium 19,000 anti-Xa IU. Single dose, disposable prefilled glass syringes of 0.6 mL (graduated process blue syringes, 11,400 anti-Xa IU; 0.8 mL (graduated magenta syringes), 15,200 anti-Xa IU; and 1 mL (graduated reflex blue syringes), 19,000 anti-Xa IU.

Who should NOT take this medication?

Do not use this mediction if you:

  • are allergic to nadroparin or to any of the ingredients of the medication
  • are allergic to other low-molecular-weight heparins or heparin
  • currently have or have previously had heparin-induced thrombocytopenia (decrease in the number of platelets), or test positive in a platelet-aggregation test while using nadroparin
  • have a history of bleeding in the brain
  • have a severe blood clotting disorder
  • have active bleeding, bleeding tendencies, or other conditions that could have an increased risk of bleeding
  • have acute infective endocarditis (bacterial infection of the heart)
  • have bleeding due to ulcers (e.g., active stomach or duodenal ulcers)
  • have eye problems due to diabetes or bleeding
  • have injuries to and have had operations on the brain, spinal cord, eyes, or ears
  • have severe kidney problems (unless you are using nadroparin to prevent clot formation during dialysis)
  • have uncontrolled high blood pressure
  • received spinal anaesthesia and need many doses of nadroparin



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