Brand Name
Lyrica
Common Name
pregabalin
In this drug factsheet:
DIN (Drug Identification Number)| 02268450 | LYRICA 150 MG CAPSULE |
| 02268418 | LYRICA 25 MG CAPSULE |
| 02268485 | LYRICA 300 MG CAPSULE |
| 02268426 | LYRICA 50 MG CAPSULE |
| 02268434 | LYRICA 75 MG CAPSULE |
| 02268477 | LYRICA 225MG CAPSULE |
How does this medication work? What will it do for me?
Pregabalin belongs to the class of medication known as analgesics. It is used to relieve neuropathic pain associated with diabetic peripheral neuropathy (pain from damaged nerves due to diabetes) and postherpetic neuralgia (persisting pain following healing of the rash due to shingles).
Pain from damaged nerves may feel sharp, burning, tingling, shooting, or numb. Pregabalin is also used to relieve pain associated with fibromyalgia (pain in the muscles, ligaments and tendons).
It may also be useful in managing central neuropathic pain (pain from damaged nerves of the brain and spinal cord). Pregabalin has been approved to treat central neuropathic pain, pending the results of studies to verify its clinical benefit.
It is not known exactly how pregabalin works, but it is thought to work in the brain to decrease the release of chemicals responsible for pain. For some people, improvement in pain may occur as early as the first week of treatment with pregabalin.
Your doctor may have suggested this medication for conditions other than those listed in these drug information articles. As well, some forms of this medication may not be used for all of the conditions discussed here. If you have not discussed this with your doctor or are not sure why you are taking this medication, speak to your doctor. Do not stop taking this medication without consulting your doctor.
Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take this medication if their doctor has not prescribed it.
How should I use this medication?
To treat neuropathic pain associated with diabetic neuropathy and postherpetic neuralgia, the recommended adult starting dose of pregabalin is 150 mg per day, given in 2 or 3 divided doses (e.g., 75 mg twice a day or 50 mg 3 times a day) with or without food.
To treat neuropathic pain associated with the central nervous system, the recommended adult starting dose of pregabalin is 150 mg per day, given in 2 divided doses (e.g., 75 mg twice a day) with or without food.
To treat pain associated with fibromyalgia, the recommended adult starting dose of pregabalin is 150 mg per day, given in 2 or 3 divided doses (e.g., 75 mg twice a day or 50 mg 3 times a day ) with or without food.
After one week of treatment, your doctor may increase the dose of pregabalin to 300 mg per day, given in 2 divided doses (e.g., 150 mg twice a day). The maximum recommended daily dose of pregabalin is 600 mg.
Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.
It is important that this medication be taken exactly as prescribed by your doctor. If you miss a dose of this medication by a few hours, take it as soon as possible and continue your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.
Store this medication at room temperature in the original packaging and keep it out of the reach of children.
Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.
What form(s) does this medication come in?
25 mg
Each white, hard gelatin capsule, printed with black ink "Pfizer" on the cap, "PGN 25" on the body contains 25 mg of pregabalin. Nonmedicinal ingredients: lactose monohydrate, maize starch, and talc; capsule shell: colloidal silicon dioxide (manufacturing aid, which may not be present), gelatin, sodium lauryl sulfate, and titanium dioxide; black ink: black iron oxide, potassium hydroxide, propylene glycol, shellac, and water.
50 mg
Each white, hard gelatin capsule, printed with black ink "Pfizer" on the cap, "PGN 50" and an ink band on the body contains 50 mg of pregabalin. Nonmedicinal ingredients: lactose monohydrate, maize starch, and talc; capsule shell: colloidal silicon dioxide (manufacturing aid, which may not be present), gelatin, sodium lauryl sulfate, and titanium dioxide; black ink: black iron oxide, potassium hydroxide, propylene glycol, shellac, and water.
75 mg
Each white-orange, hard gelatin capsule, printed with black ink "Pfizer" on the cap, "PGN 75" on the body contains 75 mg of pregabalin. Nonmedicinal ingredients: lactose monohydrate, maize starch, and talc; orange capsule shell: gelatin, red iron oxide, and titanium dioxide; white capsule shell: colloidal silicon dioxide (manufacturing aid, which may not be present), gelatin, sodium lauryl sulfate, and titanium dioxide; black ink: black iron oxide, potassium hydroxide, propylene glycol, shellac, and water.
150 mg
Each white, hard gelatin capsule, printed with black ink "Pfizer" on the cap, "PGN 150" on the body contains 150 mg of pregabalin. Nonmedicinal ingredients: lactose monohydrate, maize starch, and talc; capsule shell: colloidal silicon dioxide (manufacturing aid, which may not be present), gelatin, sodium lauryl sulfate, and titanium dioxide; black ink: black iron oxide, potassium hydroxide, propylene glycol, shellac, and water.
225 mg
Each white, light orange hard gelatin capsule, printed with black ink "Pfizer" on the cap, "PGN 225" on the body contains 225 mg pregabalin. Nonmedicinal ingredients: lactose monohydrate, maize starch, and talc; orange capsule shell: red iron oxide, gelatin, and titanium dioxide; white capsule: sodium lauryl sulfate, colloidal silicon dioxide (manufacturing aid, which may not be present), gelatin, and titanium dioxide; black ink: shellac, black iron oxide, propylene glycol, potassium hydroxide, and water.
300 mg
Each white-orange, hard gelatin capsule, printed with black ink "Pfizer" on the cap, "PGN 300" on the body contains 300 mg of pregabalin. Nonmedicinal ingredients: lactose monohydrate, maize starch, and talc; orange capsule shell: gelatin, red iron oxide, and titanium dioxide; white capsule shell: colloidal silicon dioxide (manufacturing aid, which may not be present), gelatin, sodium lauryl sulfate, and titanium dioxide; black ink: black iron oxide, potassium hydroxide, propylene glycol, shellac, and water.
Who should NOT take this medication?
Pregabalin should not be taken by anyone who is allergic to pregabalin or to any of the ingredients of the medication.