Brand Name
PMS-Diclofenac
Common Name
diclofenac
In this drug factsheet:
DIN (Drug Identification Number)| 02231505 | PMS-DICLOFENAC SR 100MG EXTENDED-RELEASE TABLET |
| 02231508 | PMS-DICLOFENAC 100MG SUPPOSITORY |
| 02231502 | PMS-DICLOFENAC 25MG ENTERIC-COATED TABLET |
| 02231506 | PMS-DICLOFENAC 50MG SUPPOSITORY |
| 02231503 | PMS-DICLOFENAC 50MG ENTERIC-COATED TABLET |
| 02231504 | PMS-DICLOFENAC SR 75MG EXTENDED-RELEASE TABLET |
| 02239753 | PMS-DICLOFENAC K 50MG TABLET |
| 02302616 | PMS-DICLOFENAC 25MG DELAYED-RELEASE TABLET |
| 02302624 | PMS-DICLOFENAC 50MG DELAYED-RELEASE TABLET |
How does this medication work? What will it do for me?
Diclofenac belongs to the class of medications known as non-steroidal anti-inflammatories (NSAIDs). It is used to reduce pain, swelling, and inflammation.
The diclofenac sodium tablet and suppository are used to relieve pain for people with rheumatoid arthritis, osteoarthritis, and degenerative joint diseases of the hip. The diclofenac potassium tablets are used for short-term relief of pain and inflammation, such as pain caused by sprains, surgery, or dental work. The eye drop is used to reduce eye inflammation before and after eye surgery (e.g., cataract surgery) and in other cases of eye inflammation where infection is not present.
Your doctor may have suggested this medication for conditions other than those listed in these drug information articles. As well, some forms of this medication may not be used for all of the conditions discussed here. If you have not discussed this with your doctor or are not sure why you are being given this medication, speak to your doctor. Do not stop using this medication without consulting your doctor.
Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to use this medication if their doctor has not prescribed it.
How should I use this medication?
Tablets: The usual adult dosage ranges from 75 mg to 150 mg daily. The immediate release diclofenac sodium tablets are taken in 3 equally divided doses with food, the diclofenac potassium tablets are taken every 6 to 8 hours with food, and the long-acting (sustained release, or SR) tablets are taken in 1 or 2 daily doses with food or milk. The maximum recommended daily dose of diclofenac is 150 mg.
Suppositories: The suppositories are usually used as a substitute for the last daily dose in a 50 mg or 100 mg strength, to a maximum total daily dose of 150 mg of diclofenac.
Eye drops: For inflammation, it is recommended that one drop be put into the eye 4 to 5 times daily. For surgery, the eye drops are used as follows:
- In the 3 hours before the surgery, one drop is put into the eye up to a maximum of 5 times.
- In the first 45 minutes after surgery, one drop is put into the eye every 15 minutes.
- After this, one drop may be put into the eye 3 to 5 times daily as needed.
Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are using the medication without consulting your doctor.
It is important to use this medication exactly as prescribed by your doctor. If you miss a dose, administer it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not administer a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.
This medication is available under multiple brand names and in several different forms. Any specific brand name of this medication may not be available in all of the forms listed here. The forms available for the specific brand you have searched are listed under "What form(s) does this medication come in?"
Store this medication at room temperature, protect it from moisture, and keep it out of the reach of children.
Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.
What form(s) does this medication come in?
Tablets
25 mg enteric-coated tablet
Each yellow, round, biconvex, bevelled-edged, enteric-coated tablet, printed with "P" in black on one side and "25" on the other side contains 25 mg diclofenac sodium. Nonmedicinal ingredients: black ink, castor oil derivatives, colloidal silicon dioxide, corn starch, hypromellose, iron oxides, lactose, magnesium stearate, microcrystalline cellulose, polyethylene glycol, povidone, sodium starch glycolate, talc, and titanium dioxide.
50 mg enteric-coated tablet
Each light brown, round, biconvex, bevelled-edged, enteric-coated tablet printed with "P" in black on one side and "50" on the other side contains 50 mg diclofenac sodium. Nonmedicinal ingredients: black ink, castor oil derivatives, colloidal silicon dioxide, corn starch, hypromellose, iron oxides, lactose, magnesium stearate, microcrystalline cellulose, polyethylene glycol, povidone, sodium starch glycolate, talc, and titanium dioxide.
25 mg delayed-release tablet
Each yellow, round, slightly biconvex, enteric coated tablet ink-printed in black with "P" on one side and "25" on the other side contains 25 mg diclofenac sodium. Nonmedicinal ingredients: colloidal silicon dioxide, FD&C Yellow No. 5, hydroxypropyl methyl cellulose, iron oxide red, iron oxide yellow, lactose, magnesium stearate, methacrylic acid polymer, microcrystalline cellulose, pharmaceutical grade black ink, polyethylene glycol, polysorbate 80, povidone, sodium hydroxide, sodium starch glycolate, talc, and titanium dioxide.
50 mg delayed-release tablet
Each light brown, round, slightly biconvex, enteric-coated tablet ink-printed in black with "P" on one side and "50" on the other side contains 50 mg diclofenac sodium. Nonmedicinal ingredients: colloidal silicon dioxide, hydroxypropyl methyl cellulose, iron oxide red, iron oxide yellow, lactose, magnesium stearate, methacrylic acid polymer, microcrystalline cellulose, pharmaceutical grade black ink, polyethylene glycol, polysorbate 80, povidone, sodium hydroxide, sodium starch glycolate, talc, and titanium dioxide.
SR 75 mg extended-release tablet
Each pale-pink, triangular, biconvex and bevelled-edged, film-coated tablet printed with "P" in black on one side and "SR/75" on the other contains 75 mg diclofenac sodium. Nonmedicinal ingredients: black ink, carnauba wax, cellulose compounds, cetyl alcohol, colloidal silicon dioxide, hypromellose, magnesium stearate, polysorbate 80, povidone, red iron oxide, sucrose, talc, and titanium dioxide.
SR 100 mg extended-release tablet
Each pink, round, biconvex, bevelled-edged, film-coated tablet, printed with "P" in black on one side and "SR/100" on the other contains 100 mg diclofenac sodium. Nonmedicinal ingredients: black ink, carnauba wax, cellulose compounds, cetyl alcohol, colloidal silicon dioxide, hypromellose, magnesium stearate, polysorbate 80, povidone, red iron oxide, sucrose, talc, and titanium dioxide.
K 50 mg tablet
Each reddish-brown, round, biconvex, sugar-coated tablet, with "50-K'' printed in white on one side and "P" logo on the other contains 50 mg diclofenac potassium. Nonmedicinal ingredients: carnauba wax, cellulose, colloidal silicon dioxide, corn starch, ferric oxide, magnesium stearate, polyethylene glycol, povidone, sodium carboxymethyl starch, sucrose, talc, titanium dioxide, tribasic calcium phosphate, and white ink.
Suppositories
50 mg rectal suppository
Each white to yellowish, torpedo-shaped suppository with a smooth surface contains 50 mg diclofenac sodium. Nonmedicinal ingredients: semi-synthetic glycerides.
100 mg rectal suppository
Each white to yellowish, torpedo-shaped suppository with a smooth surface contains 100 mg diclofenac sodium. Nonmedicinal ingredients: semi-synthetic glycerides.
Who should NOT take this medication?
Diclofenac should not be used by anyone who:
- is allergic to diclofenac or to any of the ingredients of the medication
- is breast-feeding
- is currently taking other NSAIDs
- is in the third trimester of pregnancy (after 28 weeks)
- is planning to have or recently had heart bypass surgery
- is under 16 years of age
- currently has or recently had inflammatory diseases of the stomach and intestines, such as stomach or intestinal ulcer or ulcerative colitis
- has bleeding in the brain or a bleeding disorder
- has had an allergic reaction to ASA or other anti-inflammatory medications
- has high levels of potassium in the blood
- has severe uncontrolled heart failure
- has severely impaired or deteriorating kidney function
- has significant liver impairment or liver disease
Diclofenac suppositories should not be used by anyone who:
- has any inflammatory lesions of the rectum or anus
- has recently had rectal or anal bleeding
