In this drug factsheet:DIN (Drug Identification Number)
|01913654 ||APO GLYBURIDE 2.5MG TABLET|
|01913662 ||APO GLYBURIDE 5MG TABLET|
How does this medication work? What will it do for me?
Glyburide is an antidiabetes medication that belongs to the family of medications known as sulfonylureas. It is used to treat high blood sugar (hyperglycemia) in people with type 2 diabetes.
Antidiabetes medications such as glyburide are used when diet, exercise, and weight reduction have not been found to lower blood sugar well enough on their own. Glyburide increases the release of insulin (a hormone produced by the pancreas that allows sugar to enter into cells where it is needed for energy) and helps the body use insulin more efficiently.
This medication may be available under multiple brand names and/or in several different forms. Any specific brand name of this medication may not be available in all of the forms or approved for all of the conditions discussed here. As well, some forms of this medication may not be used for all of the conditions discussed here.
Your doctor may have suggested this medication for conditions other than those listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are taking this medication, speak to your doctor. Do not stop taking this medication without consulting your doctor.
Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take this medication if their doctor has not prescribed it.
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How should I use this medication?
The recommended adult starting dose of glyburide is usually 5 mg daily (2.5 mg for patients over 60 years of age) and increases or decreases by 2.5 mg every 5 to 7 days until blood sugar is controlled. The recommended adult dose of glyburide ranges from 2.5 mg once daily to 10 mg twice daily. The maximum dose of glyburide is 20 mg daily.
Glyburide should be taken during or immediately after a meal, usually with breakfast or the first main meal of the day. If you eat only a light breakfast, wait until lunchtime to take your morning dose.
Many things can affect the dose of a medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.
Low blood sugar (hypoglycemia) is an important concern if too much of this medication is taken. Ask your doctor or diabetes educator what you should do when you are not going to be eating for a long period of time or when you are going to be exercising more than usual.
It is very important to monitor blood sugar levels closely, especially when increasing and decreasing doses of medication or when exercise level or weight changes occur. Your doctor or diabetes educator will instruct you on the best use of a diabetes monitor.
It is important to take this medication exactly as prescribed by your doctor. If you miss a dose, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.
Store this medication at room temperature, protect it from light and moisture and keep it out of reach of children.
Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.
What form(s) does this medication come in?
Each white, round tablet, flat-faced with bevelled edges, scored and identified "APO" over "2.5" on one side, contains glyburide 2.5 mg. Nonmedicinal ingredients: croscarmellose sodium, lactose, magnesium stearate, and microcrystalline cellulose.
Each white, capsule-shaped tablet, flat-faced with bevelled edges, scored on one side and identified "APO 5" on the other side, contains glyburide 5 mg. Nonmedicinal ingredients: croscarmellose sodium, lactose, magnesium stearate, and microcrystalline cellulose.
Who should NOT take this medication?
Do not take glyburide if you:
- are allergic to glyburide or any ingredients of the medication
- are allergic to sulfonylurea or sulphonamide medictions
- are breast-feeding or pregnant
- are in a diabetic coma or pre-coma (a result of hypoglycemia - symptoms include speech and visual disturbances, flushing, trembling, headache, nausea, vomiting)
- are taking the medication bosentan
- are undergoing surgery or has recently suffered severe trauma (a loss of blood sugar control may occur and insulin administration may be required)
- have diabetic ketoacidosis with or without coma
- have a serious infection (a loss of blood sugar control may occur and insulin administration may be required)
- have jaundice
- have serious kidney or liver impairment
- have type 1 diabetes