Brand Name
Nytol
Common Name
diphenhydramine (sleep aid)
In this drug factsheet:
DIN (Drug Identification Number)| 02237169 | EXTRA STRENGTH NYTOL QUICKGELS |
| 00450839 | NYTOL TABLET 25MG |
| 01934414 | NYTOL 50MG EX STRENGTH CAPLET |
| 00583332 | EXTRA STRENGTH NYTOL TAB 50MG |
How does this medication work? What will it do for me?
Diphenhydramine belongs to a group of medications known as antihistamines. Antihistamines are used to treat symptoms caused by allergies, including itchy and watery eyes, sneezing, runny nose, and skin irritation. Diphenhydramine also causes drowsiness, and can be used by adults and children 12 years of age and older who have trouble sleeping (insomnia).
If you have trouble sleeping, do not use this medication for more than a few nights in a row. Talk to your doctor about other treatment options suitable for you if you have chronic (long-term) insomnia that persists for more than a few nights at a time.
Your doctor may have suggested this medication for conditions other than the ones listed in these drug information articles. As well, some forms of this medication may not be used for all of the conditions discussed here. If you have not discussed this with your doctor or are not sure why you are taking this medication, speak to your. Do not stop taking this medication without consulting your doctor.
Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take this medication if their doctor has not prescribed it.
How should I use this medication?
The usual dose for adults and children 12 years of age and older to help with sleep is 25 mg to 50 mg taken by mouth at bedtime. Some people may only need to take 25 mg at bedtime if they are drowsy in the morning (e.g., they find it interferes with their daily activities), after taking the 50 mg dose.
Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones above, do not change the way that you are taking the medication without consulting your doctor.
It is important to use this medication exactly as prescribed by your doctor.
Store this medication at room temperature and keep it out of the reach of children.
Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.

What form(s) does this medication come in?
Tablets
25 mg
Each white, uncoated tablet, imprinted with an "N" on one side, contains diphenhydramine HCl 25 mg. Nonmedicinal ingredients: cornstarch, lactose, microcrystalline cellulose, silicon dioxide, and stearic acid.
50 mg
Each blue, uncoated tablet, imprinted with an "N" on one side, contains diphenhydramine HCl 50 mg. Nonmedicinal ingredients: cornstarch, FD&C Blue No. 1 Aluminum Lake, lactose, microcrystalline cellulose, silicon dioxide, and stearic acid.
Caplets: Extra Strength
Each blue, coated caplet, imprinted with "Nytol" on one side, contains diphenhydramine HCl 50 mg. Nonmedicinal ingredients: cornstarch, FD&C Blue No. 1 Aluminum Lake, lactose, microcrystalline cellulose, Opadry light blue YS-1-4004, silicon dioxide, and stearic acid.
Capsules: Extra Strength Quickgels
Each clear, light yellow, soft gel capsule, imprinted with a white "N" on one side, contains diphenhydramine HCl 50 mg. Nonmedicinal ingredients: edible ink, gelatin, glycerin, polyethylene glycol, sorbitol, and water.
Some medications may have other generic brands available. Always ask your doctor or pharmacist about the safety of switching between brands of the same medication.
Who should NOT take this medication?
This medication should not be used by anyone who:
- is allergic to diphenhydramine or to any of the ingredients of the medication
- has asthma or chronic lung disease
- has an enlarged prostate
- has an obstructed bladder
- have certain stomach conditions (e.g., stenosing peptic ulcer or pyloroduodenal obstruction)
- has glaucoma
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