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Drug Info > O > Orgalutran
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DIN (Drug Identification Number)


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Brand Name


Common Name
ganirelix injection

In this drug factsheet:

DIN (Drug Identification Number)


How does this medication work? What will it do for me?

Ganirelix belongs to the class of medications known as gonadotropin-releasing hormone (GnRH) antagonists. It is used to prevent premature ovulation in women undergoing ovarian stimulation as part of fertility treatment. It blocks the effects of gonadotropin-releasing hormone (GnRH).

GnRH controls the secretion of another hormone, called luteinizing hormone (LH), a hormone that starts ovulation (release of an egg) during the menstrual cycle. Ganirelix allows the release of an egg to be controlled so it is released at the best time for pregnancy to occur.

Your doctor may have suggested this medication for conditions other than those listed in these drug information articles. As well, some forms of this medication may not be used for all of the conditions discussed here. If you have not discussed this with your doctor or are not sure why you are taking this medication, speak to your doctor. Do not stop taking this medication without consulting your doctor.

Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take this medication if their doctor has not prescribed it.

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How should I use this medication?

The usual dose of ganirelix is 250 µg injected once daily under the skin. The length of treatment is usually about 5 days, but can range from 1 to 19 days. Ganirelix should be injected under the skin of the upper thigh, as directed by your doctor.

A health care professional will show you how to use this medication properly. Read the patient information leaflet carefully and ask your doctor any questions you may have.

Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.

It is important to use this medication exactly as prescribed by your doctor. If you miss a dose, administer it as soon as possible. If you are more than 6 hours late (i.e., the time between 2 injections is longer than 30 hours), give the dose as soon as possible and contact your doctor for further instruction. Do not inject a double the dose to make up for a missed dose. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.

Store this medication at room temperature between 15°C and 30°C, protect it from light, and keep it out of the reach of children.

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.

What form(s) does this medication come in?

Each prefilled syringe of clear, colourless, sterile, ready-to-use solution contains ganirelix 250 µg. Nonmedicinal ingredients: acetic acid and/or sodium hydroxide to adjust pH, glacial acetic acid, mannitol, and water for injection.

Who should NOT take this medication?

Do not use this medication if you:

  • are allergic to ganirelix, gonadotropin-releasing hormone (GnRH), other GnRH-related hormones, or any of the ingredients of the medication or the container (such as latex)
  • are or may be pregnant
  • have moderate-to-severe liver or kidney function impairment



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