calcipotriol - betamethasone
In this drug factsheet:
How does this medication work? What will it do for me?
This is a combination product that contains 2 medications: calcipotriol and betamethasone. This medication is used to treat psoriasis. Calcipotriol belongs to the class of medications known as vitamin D analogues and works by controlling the excessive production of skin cells seen in psoriasis. Betamethasone belongs to the class of medications known as corticosteroids and works by reducing itching and inflammation.
The ointment form of this medication is used to treat psoriasis that develops on the skin. The gel form of this medication is used to treat psoriasis that has developed on the scalp and body.
This medication may be available under multiple brand names and/or in several different forms. Any specific brand name of this medication may not be available in all of the forms or approved for all of the conditions discussed here. As well, some forms of this medication may not be used for all of the conditions discussed here.
Your doctor may have suggested this medication for conditions other than those listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are being given this medication, speak to your doctor. Do not stop using this medication without consulting your doctor.
Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to use this medication if their doctor has not prescribed it.
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How should I use this medication?
The ointment or gel is applied once daily to affected areas and gently rubbed in. Do not apply the medication to areas that do not have psoriasis.
The maximum adult weekly dose of ointment and gel combined is 100 g. The recommended treatment period is 4 weeks for the ointment, and up to 8 weeks for the gel if used on the body. Most people will notice a benefit during this time. Some people may require treatment for longer than 4 weeks. The medication can be stopped once a satisfactory improvement is achieved.
Calcipotriol - betamethasone gel should not be applied from 12 hours before to 12 hours after chemical hair treatments such as dyes or perms.
After applying the medication to the affected areas, do not wash it off. The medication needs to stay in contact with the affected areas in order to work.
Do not apply this medication on the face, large areas of damaged skin, in skin folds, or under dressings that do not breathe. Wash your hands after applying calcipotriol - betamethasone so that you do not get the ointment or gel on other parts of your body. Avoid getting the medication in your eyes or on your face. If the medication gets on your face, wash it off. If it gets in your eyes, flush the eyes with plenty of water. Do not take this medication by mouth.
Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are using the medication without consulting your doctor.
It is important to use this medication exactly as prescribed by your doctor. If you miss a dose, apply it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not apply more than one dose on any given day. Do not apply a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.
Do not use the ointment from any tube that has been open for longer than 12 months. Do not use the gel from any bottle that has been open for longer than 3 months.
Store this medication at room temperature and keep it out of the reach of children.
Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.
What form(s) does this medication come in?
Each g of faintly translucent white to yellowish ointment contains calcipotriol 50 µg plus betamethasone (as dipropionate) 0.5 mg. Nonmedicinal ingredients: α-tocopherol, liquid paraffin, polyoxypropylene-15-stearyl ether, and white soft paraffin.
Each g of almost clear, colourless to slightly off-white gel contains calcipotriol 50 µg plus betamethasone (as dipropionate) 0.5 mg. Nonmedicinal ingredients: liquid paraffin, polyoxypropylene-15-stearyl ether, hydrogenated castor oil, α-tocopherol, and butylhydroxytoluene.
Who should NOT take this medication?
Do not use this medication if you:
- are allergic to calcipotriol, betamethasone, or any ingredients of this medication
- have a disorder related to calcium metabolism
- have perioral dermatitis (skin lesions around the mouth), ichthyosis (dry, scaly skin), acne, rosacea, ulcers, or broken skin
- have severe forms of psoriasis (e.g., guttate, exfoliative, erythrodermic and pustular psoriasis)
- have severe kidney dysfunction
- have severe liver dysfunction
- have skin eruptions after receiving a vaccination
- have thin skin, easily damaged veins, or stretch marks
- have tuberculosis skin lesions or skin infections related to syphilis
- have viral diseases such as herpes simplex, varicella (chickenpox), and vaccinia
- have viral, fungal, or bacterial skin infections
Do not use this medication in or around your eyes.