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Drug Info > R > Ratio-Cotridin
Please enter the drug name or
DIN (Drug Identification Number)


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Brand Name


Common Name
codeine - triprolidine - pseudoephedrine

In this drug factsheet:

DIN (Drug Identification Number)


How does this medication work? What will it do for me?

This combination product contains three medications: codeine, triprolidine, and pseudoephedrine.

Codeine belongs to the group of medications called narcotic analgesics and cough suppressants.

Triprolidine belongs to the group of medications called antihistamines, and helps to relieve sneezing and runny nose.

Pseudoephedrine belongs to the group of medications called nasal decongestants, and reduces nasal congestion.

Codeine - triprolidine - pseudoephedrine is used to treat coughs related to inflamed tissues in the nose and throat. It works by reducing inflammation in the nose and throat tissues and decreasing cough.

Your doctor may have suggested this medication for conditions other than those listed in these drug information articles. As well, some forms of this medication may not be used for all of the conditions discussed here. If you have not discussed this with your doctor or are not sure why you are taking this medication, speak to your doctor. Do not stop taking this medication without consulting your doctor.

Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take this medication if their doctor has not prescribed it.

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How should I use this medication?

The recommended dose for adults and adolescents 12 years and over is 10 mL (2 teaspoons) or 1 tablet, every 4 to 6 hours as needed.

The recommended dose for children 6 to 12 years old is 5 mL (one teaspoon) or one half tablet 3 to 4 times a day as needed.

The recommended dose for children 2 to 6 years is 2.5 mL (one-half teaspoon) or one quarter tablet 3 to 4 times a day as needed.

In all cases, no more than 4 doses should be taken in a 24-hour period.

Many things can affect the dose of a medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.

Use an oral syringe to measure each dose of the liquid, as it gives a more accurate measurement than household teaspoons.

It is important to take this medication exactly as prescribed by your doctor. If your doctor has told you to take this medication on a regular basis and you miss a dose, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.

Store this medication at room temperature, protect it from light and moisture, and keep it out of the reach of children.

This medication is available under multiple brand names and/or in several different forms. Any specific brand name of this medication may not be available in all of the forms listed here. The forms available for the specific brand you have searched are listed under "What form(s) does this medication come in?"

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.

What form(s) does this medication come in?

Each 5 mL of red syrupy liquid with a cherry odour contains triprolidine HCl 2 mg, pseudoephedrine HCl 30 mg, and codeine phosphate 10 mg. Nonmedicinal ingredients: artificial colouring and flavourings, glycerin, methylparaben, propylparaben, purified water, sorbitol, and sucrose.

Who should NOT take this medication?

Do not use this medication if you:

  • are allergic to codeine, triprolidine, pseudoephedrine, or any of the ingredients of the medication
  • are allergic to codeine-like narcotics, other similar antihistamines, or decongestants
  • are taking an MAO inhibitor (e.g., phenelzine, tranylcypromine) or have taken one in the past 2 weeks
  • are 12 years of age or younger
  • have a head injury or increased pressure inside the brain
  • have an ongoing or persistent cough
  • have decreased kidney function
  • have pheochromocytoma (a type of adrenal gland tumour)
  • have severe coronary artery disease
  • have severe high blood pressure
  • have severely reduced liver function
  • have ulcerative colitis (inflammation of the digestive tract)

This medication should not be given to newborn or premature infants.



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