In this drug factsheet:DIN (Drug Identification Number)
|01907123 ||ISOPTIN SR EXTENDED-RELEASE 120MG TABLET|
|01934317 ||ISOPTIN SR EXTENDED-RELEASE 180MG TABLET|
|00742554 ||ISOPTIN SR EXTENDED-RELEASE 240MG TABLET|
How does this medication work? What will it do for me?
Verapamil belongs to the class of medications called calcium channel blockers. The sustained release (SR) form of this medication is used for the treatment of mild-to-moderate high blood pressure, when beta-blockers or diuretics (water pills) are not recommended or have caused unacceptable side effects. The immediate-release form of verapamil may be used to treat certain abnormal heart rhythms, angina (chest pain) and certain conditions where the heart muscle is enlarged, as well as blood pressure. It works to control blood pressure and reduce the number of angina attacks by relaxing blood vessels. It also helps to normalize heart rhythms.
This medication may be available under multiple brand names and/or in several different forms. Any specific brand name of this medication may not be available in all of the forms or approved for all of the conditions discussed here. As well, some forms of this medication may not be used for all of the conditions discussed here.
Your doctor may have suggested this medication for conditions other than those listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are taking this medication, speak to your doctor. Do not stop taking this medication without consulting your doctor.
Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take this medication if their doctor has not prescribed it.
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How should I use this medication?
For most conditions, the dose of verapamil for adults is 80 mg to 120 mg taken 3 or 4 times daily with food. This dose may be increased to a maximum of 480 mg daily. When treating specific conditions where the heart muscle is enlarged and preventing the heart from working efficiently, the dose may be increased to 600 mg or 720 mg of verapamil divided throughout the day.
If you use the sustained-release (SR) tablets, the recommended dose of verapamil ranges from 180 mg to 480 mg daily with food. The SR tablets are to be taken once daily if the dose is 240 mg or less. Doses over 240 mg daily of the SR tablets should be taken in 2 divided doses (morning and evening) with food. Do not chew or crush the sustained-release tablets. Do not take more than 480 mg daily.
Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.
It is important to take this medication exactly as prescribed by the doctor. If you miss a dose, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.
Store this medication at room temperature, protect it from light and moisture, and keep it out of the reach of children.
Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.
What form(s) does this medication come in?
Each white, biconvex, round, film-coated tablet, with "120 SR" embossed on one side, "KNOLL" on the other side, contains verapamil HCl 120 mg. Nonmedicinal ingredients: hydroxypropyl methylcellulose, macrogol 400, macrogol 6000, magnesium stearate, microcrystalline cellulose, montan glycol wax, povidone, purified water, sodium alginate, talc, and titanium dioxide.
Each old rose, oval, film-coated tablet with "KNOLL" on one side and "SR", score, "180" on the other contains verapamil HCl 180 mg. Nonmedicinal ingredients: hydroxypropyl methylcellulose, macrogol 400, macrogol 6000, magnesium stearate, microcrystalline cellulose, montan glycol wax, povidone, purified water, red iron oxide, sodium alginate, talc, and titanium dioxide.
Each light-green, scored, oblong, film-coated tablet, with 2 triangles embossed on one side, contains verapamil HCl 240 mg. Nonmedicinal ingredients: hydroxypropyl methylcellulose, indigo carmine, macrogol 400, macrogol 6000, magnesium stearate, microcrystalline cellulose, montan glycol wax, povidone, purified water, quinoline yellow, sodium alginate, talc, and titanium dioxide.
Who should NOT take this medication?
Do not use verapamil if you:
- are allergic to verapamil or any ingredients of this medication
- are suffering from severe congestive heart failure and/or severe left ventricular dysfunction unless it is due to a cause that is treatable by verapamil
- have a very low heart rate
- have certain types of abnormal heart rhythms, including atrial flutter or atrial fibrillation and an accessory bypass tract (e.g., Wolff-Parkinson-White, Lown-Ganong-Levine syndromes)
- have severe low blood pressure
- have second- or third-degree heart block or sick sinus syndrome
This medication should not be given to people who are in cardiogenic shock or those who are suffering from certain types of complicated heart attack.