Brand Name
Tussionex
Common Name
phenyltoloxamine - hydrocodone
In this drug factsheet:
DIN (Drug Identification Number)| 01916971 | TUSSIONEX SUSPENSION |
| 01916963 | TUSSIONEX TABLET SA |
How does this medication work? What will it do for me?
This medication contains two medicinal ingredients: hydrocodone and phenyltoloxamine.
Hydrocodone belongs to the class of medications called antitussives (cough
suppressants). Phenyltoloxamine belongs to the class of medications called antihistamines.
These two ingredients work together for the treatment of exhausting or non-productive
cough that is associated with cold or with upper respiratory allergic conditions.
Relief from the symptoms of coughing usually lasts between 8 to 12 hours. Hydrocodone
is a narcotic medication This medication is normally prescribed only
after non-narcotic medications have been found ineffective.
Your doctor may have suggested this medication for conditions other than the
ones listed in these drug information articles. If you have not discussed this
with your doctor or are not sure why you are taking this medication, speak to
your doctor. Do not stop taking this medication without consulting your doctor.
How should I use this medication?
Adults: The usual adult dose is 5 mL or 1 tablet every 8 to 12 hours.
The maximum daily dose is 10 mL or 2 tablets.
Children (suspension): For children 1 to 5 years of age, the recommended
dose is 2.5 mL every 12 hours, with a maximum daily dose of 5 mL.
For children over 5 years, the recommended dose is 5 mL every 12 hours,
with a maximum daily dose of 10 mL. This medication is not recommended
for children under one year of age weighing less than 9 kg.
Shake this preparation well. Do not dilute with fluids or mix with other medication.
Many things can affect the dose of medication that a person needs, such as
body weight, other medical conditions, and other medications. If your doctor
has recommended a dose different from the ones listed here, do not change
the way that you are taking the medication without consulting your doctor.
This medication has the potential to become habit-forming if used regularly
for long periods of time. It should be used exactly as prescribed by the doctor.
Do not take more of this medication than prescribed. If you miss a dose of the
scheduled medication, take it as soon as you remember. Leave at least eight
hours between doses of this medication.
Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.

What form(s) does this medication come in?
Suspension
Each 5 mL of neutral tasting, gold-coloured, thixotropic suspension, contains hydrocodone resin complex equivalent to hydrocodone bitartrate 5 mg and phenyltoloxamine resin complex equivalent to phenyltoloxamine citrate 10 mg. Nonmedicinal ingredients: ethanol, FD&C yellow No. 6, FD&C yellow No. 10, glycerin, methylparaben, peach flavour, pineapple flavour, propylene glycol, propylparaben, sorbital, water, xanthan gum.
Tablets
Each light brown tablet, scored on one side and marked 0894 on the other, contains hydrocodone resin complex equivalent to hydrocodone bitartrate 5 mg and phenyltoloxamine resin complex equivalent to phenyltoloxamine citrate 10 mg. Nonmedicinal ingredients: calcium phosphate dibasic, colloidal silicon dioxide, lactose monohydrate, magnesium stearate, starch, sugar, water.
Some medications may have other generic brands available. Always ask your doctor or pharmacist about the safety of switching between brands of the same medication.
Who should NOT take this medication?
Phenyltoloxamine - hydrocodone should not be taken by anyone who:
- takes MAO inhibitors such as phenelzine or tranylcypromine, or has taken them within the past 14 days
- is allergic to any of the ingredients of the medication
- has very high blood pressure
- has pre-existing respiratory depression
- has lesions inside the head causing increased pressure inside the head
(intracranial pressure)
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