How does this medication work? What will it do for me?
Tobramycin - dexamethasone eye drops and ointment are combination medications used for the treatment of inflammatory eye conditions where bacterial eye infection or a risk of bacterial eye infection exists.
Tobramycin belongs to the class of medications called antibiotics. It works by killing certain types of bacteria that may cause eye infections.
Dexamethasone belongs to the class of medications called corticosteroids. It helps to reduce eye irritation, redness, and inflammation.
Your doctor may have suggested this medication for conditions other than those listed in these drug information articles. As well, some forms of this medication may not be used for all of the conditions discussed here. If you have not discussed this with your doctor or are not sure why you are taking this medication, speak to your doctor. Do not stop taking this medication without consulting your doctor.
Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take this medication if their doctor has not prescribed it.
What form(s) does this medication come in?
Each mL of sterile, isotonic, aqueous suspension contains tobramycin 3 mg and dexamethasone 0.1% with benzalkonium chloride 0.01% as a preservative. Nonmedicinal ingredients: edetate disodium, hyroxyethyl cellulose, purified water, sodium chloride, sodium hydroxide and/or sulfuric acid (to adjust pH), sodium sulfate, and tyloxapol.
Each gram of sterile ophthalmic ointment contains tobramycin 3 mg and dexamethasone 0.1% with chlorobutanol 0.5% as a preservative in a mineral oil and petrolatum base.
How should I use this medication?
Drops: The usual adult dose is 1 to 2 drops instilled into the eye every 4 hours. In the first 24 to 48 hours, the dose may be increased to 1 or 2 drops every 2 hours as prescribed by your doctor. Your doctor will reduce the dose gradually based on improvement in your condition. Prevent contamination of the dropper by avoiding contact with the eye, skin, or other surfaces.
Ointment: The usual adult dose is a 1.25 cm (one-half inch) ribbon applied into the eye (along the edge of the lower eyelid) up to 3 or 4 times daily, or used in addition to the drops at bedtime. Prevent contamination of the tip of the ointment container by avoiding contact with the eye, skin, or other surfaces.
Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.
It is important to use this medication exactly as prescribed by your doctor. If you miss a dose, use it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.
Store this medication at room temperature, protect it from light and moisture, and keep it out of the reach of children.
Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.
Who should NOT take this medication?
Do not use this medication if you:
- are allergic to tobramycin, dexamethasone, or any ingredients of this medication
- have just had a foreign body (object) removed from your eye
- have tuberculosis of the eye, fungal diseases of the eye, or acute weeping untreated infections of the eye
- have vaccinia, varicella, herpes simplex, or other viral diseases of the eye
What side effects are possible with this medication?
Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.
The side effects listed below are not experienced by everyone who takes this medication. If you are concerned about side effects, discuss the risks and benefits of this medication with your doctor.
The following side effects have been reported by at least 1% of people taking this medication. Many of these side effects can be managed, and some may go away on their own over time.
Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.
- itching and swelling of eyelid
- redness of eye
Although most of the side effects listed below don't happen very often, they could lead to serious problems if you do not seek medical attention.
Check with your doctor as soon as possible if any of the following side effects occur:
- eye pain
Stop taking the medication and seek immediate medical attention if any of the following occur:
- blurring or loss of vision
Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking this medication.
Are there any other precautions or warnings for this medication?
Before you begin using a medication, be sure to inform your doctor of any medical conditions or allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use this medication.
Contact lenses: If you use contact lenses, ask your doctor about their use while using this medication.
Long-term use: Prolonged use of this medication may result in glaucoma, with damage to the optic nerve, vision problems, perforation of the cornea, and cataracts. Prolonged use of this medication may also result in overgrowth of microorganisms (e.g., certain bacteria or fungi) that are not killed by the antibiotic. If there is no improvement after 5 or 7 days of therapy or if your condition worsens, call your doctor.
Pregnancy: This medication should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking this medication, contact your doctor immediately.
Breast-feeding: It is not known if this medication passes into breast milk. If you are a breast-feeding mother and are taking this medication, it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.
Children: The safety and effectiveness of using this medication have not been established for children.
What other drugs could interact with this medication?
There may be an interaction between tobramycin - dexamethasone and any of the following:
- other eye drops containing corticosteroids (e.g. prednisolone eye drops)
If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:
- stop taking one of the medications,
- change one of the medications to another,
- change how you are taking one or both of the medications, or
- leave everything as is.
An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.
Medications other than those listed above may interact with this medication. Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.
All material copyright MediResource Inc. 1996 – 2017. Terms and conditions of use. The contents herein are for informational purposes only. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. Source: www.medbroadcast.com/drug/getdrug/Tobradex