This medication is used to treat coughs related to inflamed tissues in the nose and throat. It works by reducing inflammation in the nose and throat tissues and decreasing cough.

Your doctor may choose to use a medication for conditions other than the ones listed in these drug information articles. If you're unsure why you are taking this medication, contact your doctor.

How should I use this medication?

Adults and adolescents 12 years and over: The recommended dose is 10 mL (2 teaspoons) every four to six hours as needed (do not exceed four doses in 24 hours).

Children 6 to 12 years: The recommended dose is 5 mL (one teaspoonful) every four to six hours as needed (do not exceed four doses in 24 hours).

Children 2 to 6 years: The recommended dose is 2.5 mL (one-half teaspoonful) every four to six hours as needed (do not exceed four doses in 24 hours).

Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.

It is very important that this medication be taken as prescribed by the doctor. If you miss a dose, take it as soon as you remember it. If it is almost time for your next dose, skip the missed dose and carry on with your regular schedule. Do not double-up on doses.

This medication is available under multiple brand names and in several different forms. Any specific brand name of this medication may not be available in all of the forms listed here. The forms available for the specific brand you have searched are listed under "What form(s) does this medication come in?"

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.

Each white to off-white, biconvex tablet, code number "WELLCOME P4B" on same side as score mark, contains triprolidine HCl 4 mg, pseudoephedrine HCl 60 mg and codeine phosphate 20 mg. Nonmedicinal ingredients: cornstarch, lactose, gelatin, magnesium stearate and quinoline yellow WS. Each tablet is equivalent to 10 mL of syrup. If tablet is broken in half, it reveals a yellow core. Tartrazine-free.

This medication should not be used by:

• newborn or premature infants
• anyone allergic to codeine or other narcotics, triprolidine, other antihistamines of similar chemical structure, pseudoephedrine,or any of the ingredients of the medication
• anyone who is taking an MAO inhibitor (e.g., phenelzine, tranylcypromine) or has taken one in the past 2 weeks
• anyone with severe high blood pressure
• anyone with severe coronary artery disease

The side effects listed below are not experienced by everyone who takes this medication. If you are concerned about side effects, discuss the risks and benefits of this medication with your doctor. Your health professional may be able to help you deal with some of the effects.

The following side effects may go away as your body becomes used to the medicine; check with your doctor if they continue or become bothersome.

Less common or rare:

• constipation
• dizziness
• drowsiness
• dry mouth
• insomnia
• jitteriness
• nausea or vomiting

Other side effects not listed above may occur in some people. Check with your doctor if you notice any symptom that worries you while you are taking this medication.

Are there any other precautions or warnings for this medication?

Dependence: Codeine may be habit-forming when used over long periods or in high doses. Do not take this medication for longer, in greater amounts, or more frequently than prescribed.

Intolerance: If you take this medication, watch for signs that you are developing an intolerance to it. If you notice such symptoms, stop taking the medication and contact your doctor. Symptoms of intolerance include:

• drowsiness
• dizziness
• weakness
• difficulty breathing
• tenseness
• muscle tremors
• palpitations

Medical conditions: This preparation should be used with considerable caution by people with:

• increased eye pressure (narrow-angle glaucoma)
• certain types of stomach ulcer
• enlarged prostate
• high blood pressure
• diabetes
• ischemic heart disease
• overactive thyroid
• severe kidney or liver dysfunction
• gallbladder disease
• irregular heart rate
• asthma or other breathing troubles

Occupational hazards: While taking this medication, avoid activities requiring mental alertness such as driving a car or operating dangerous machinery until you have determined that it does not impair your ability to do such things.

Pregnancy: Pregnant women should only take this medication if clearly needed. Its use during pregnancy is not recommended.

Breast-feeding: This medication passes in small amounts into breast milk, but the significance of its effects on the nursing infant is unknown. A decision should be made whether to stop nursing or to stop the medication, taking into account the importance of the medication to the mother.

Children: This medication may cause either mild stimulation or mild sedation. Overdosage in infants and children may produce hallucinations and convulsions.

Seniors: This medication is more likely to cause side effects for those 60 years of age and older.

What other drugs could interact with this medication?

The following may affect how this medication works or increase the risk of side effects:

• alcohol
• antihistamines that cause drowsiness (e.g., diphenhydramine)
• cimetidine
• MAO inhibitors (e.g., phenelzine, tranylcypromine)
• methocarbamol
• methohexital
• phenothiazines (e.g., promethazine, perphenazine)
• quinidine
• sedatives (e.g., diazepam)
• thiopental
• tricyclic antidepressants (e.g., amitriptyline, imipramine)

This medication may affect the way that the following medications work:

• methyldopa
• reserpine

If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:

• stop taking one of the medications,
• change one of the medications to another,
• change how you are taking one or both of the medications, or
• leave everything as is.

An interaction between two medications does not always mean that you must stop taking one of them. In many cases, interactions are intended or are managed by close monitoring. Speak to your doctor about how any drug interactions are being managed or should be managed.

Medications other than those listed above may interact with this medication. Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications that you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.