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Drug Info > E > Estraderm
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DIN (Drug Identification Number)


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Brand Name

Estraderm

Common Name
estradiol patch


In this drug factsheet:



DIN (Drug Identification Number)

00756849 ESTRADERM-25 PATCH
00756792 ESTRADERM-100 PATCH

How does this medication work? What will it do for me?

Estradiol patch belongs to the class of medications known as estrogen replacement therapy. It is used for the management of menopausal symptoms such as abnormal uterine bleeding, hot flushes, sweating, and chills.

When an estradiol patch is applied to your skin, it releases estradiol into your blood through the skin. Estradiol is a type of estrogen, a female hormone that is produced by the ovaries. At menopause, the amount of estrogen made by the ovaries declines and symptoms such as hot flashes (sudden, extreme feeling of warmth) and vaginal dryness can occur. Most women reach menopause naturally around the age of 50, but some women may undergo menopause sooner due to many causes, including surgery.

Women who have not had a hysterectomy (removal of their uterus or womb) must also take another female hormone called progestin while they are taking this medication to prevent complications associated with taking estrogen alone.

Estradiol patch is also used for the prevention of osteoporosis when there are low estrogen levels in the body, in addition to other measures to help prevent osteoporosis - such as calcium and vitamin D supplements, quitting smoking, and regular weight-bearing exercise.

Your doctor may have suggested this medication for conditions other than those listed in these drug information articles. As well, some forms of this medication may not be used for all of the conditions discussed here. If you have not discussed this with your doctor or are not sure why you are being given this medication, speak to your doctor. Do not stop using this medication without consulting your doctor.

Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to use this medication if their doctor has not prescribed it.

People who read this article also read about:

How should I use this medication?

A new patch should be applied to your skin on the same days twice a week (i.e., the patch should be changed once every 3 to 4 days). Women who have not had a hysterectomy (removal of their uterus) must also take a progestin while they are taking this medication to prevent side effects associated with the use of estrogen.

The patch is often applied to the buttocks, lower back, lower abdomen, or hip. Many women have found that less skin irritation occurs when the patch is applied to the buttocks. Talk to your doctor or pharmacist about the most appropriate site to apply the patch. Do not apply the patch to your breasts. Do not apply patches to the same site on the skin twice in a row.

To apply the patch:

  1. Choose a clean and dry area of intact skin that is not oily, damaged, irritated, or exposed to the sun. To avoid irritation, do not apply to the same site on the skin 2 times in a row.
  2. Tear open the pouch containing the patch rather than using scissors - if you accidentally cut the patch, it will be useless.
  3. Remove the protective layer. Apply the patch to the selected area immediately. Avoid touching the adhesive.
  4. Use your fingers to hold the patch in place for about 10 seconds and make sure that the patch is affixed to your skin, especially around its edges.

When changing the patch, remove the old one carefully, fold it in half so that the adhesive sides stick together, and throw it away or bring it to the pharmacy for proper disposal. Keep it out of the reach of children or pets. If adhesive remains on your skin, rub it off gently.

Bathing, showering, swimming, or other contact with water does not affect the patch. However, hot water or steam may cause the patch to loosen. If your patch falls off, try to reapply it. If that doesn't work, apply a new patch.

Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are using the medication without consulting your doctor.

It is important to use this medication exactly as prescribed by your doctor. If you forget to apply or change your patch, change it as soon as you remember. If it is close to the day when you normally change your patch, still apply it but change the patch again on your usual day and continue on with your regular schedule. Do not wear 2 patches at once. If you are not sure what to do after forgetting to apply or change the patch, contact your doctor or pharmacist for advice.

Store this medication at room temperature and keep it out of the reach of children. Do not store the patches out of the pouch.

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.





What form(s) does this medication come in?

Estraderm is no longer being manufactured for sale in Canada. For brands that may still be available, search under estradiol patch. This article is being kept available for reference purposes only. If you are using this medication, speak with your doctor or pharmacist for information about your treatment options.

Who should NOT take this medication?

Do not use this medication if you:

  • are allergic to estradiol or any ingredients of this medication
  • are breast-feeding
  • are or may be pregnant
  • have, have had, or may have breast cancer
  • have a blood clotting disorder
  • have a history of known or suspected estrogen-dependent tumours (e.g., endometrial cancer)
  • have active phlebitis (inflamed varicose veins)
  • have classical migraines
  • have endometrial hyperplasia (thickening of the inner lining of the uterus)
  • have liver dysfunction or disease
  • have or have had a history of liver tumours
  • have or have had a stroke, heart attack, or coronary heart disease
  • have or have had blood clots in the legs or lungs, or coronary thrombosis
  • have partial or complete loss of vision from eye disease related to circulation problems
  • have porphyria
  • have unusual vaginal bleeding that has not been checked by a doctor


 

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