In this drug factsheet:DIN (Drug Identification Number)
|02404508 ||TECFIDERA 120 MG CAPSULE|
How does this medication work? What will it do for me?
Dimethyl fumarate is a medication that acts on the central nervous system (the brain and spinal cord). It is used to reduce how often the symptoms of relapsing-remitting multiple sclerosis (MS) occur and to slow down the progression of disability. In the relapsing-remitting form of MS, attacks of symptoms (relapses) are followed by periods when the symptoms go away completely or partially (remissions).
MS is believed to be a disease where the body creates inflammation that damages the cells in the central nervous system. When the cells in the nervous system are damaged, the ability of the brain to send messages to the rest of the body is reduced.
Although it is not completely clear how it works, dimethyl fumarate may work by changing the way the immune system works, to help prevent further damage to the cells in the brain and spinal cord.
This medication may be available under multiple brand names and/or in several different forms. Any specific brand name of this medication may not be available in all of the forms or approved for all of the conditions discussed here. As well, some forms of this medication may not be used for all of the conditions discussed here.
Your doctor may have suggested this medication for conditions other than those listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are taking this medication, speak to your doctor. Do not stop taking this medication without consulting your doctor.
Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take this medication if their doctor has not prescribed it.
How should I use this medication?
The usual starting dose of dimethyl fumarate is 120 mg taken twice a day. This is taken for the first 7 days and then the dose is increased to 240 mg (two 120 mg capsules) taken twice a day.
Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.
Dimethyl fumarate may be taken with or without food. If you experience flushing, take the medication with food to reduce this effect.
Swallow the capsules whole with water or another fluid. Do not divide, crush, dissolve, suck, or chew on the capsule.
It is important to take this medication exactly as prescribed by your doctor. If you miss a dose, take it as soon as possible and continue with your regular schedule. If it is less than 4 hours before your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.
Store this medication at room temperature, protect it from light and moisture, and keep it out of the reach of children.
Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.
What form(s) does this medication come in?
Each capsule with a green cap and white body, printed with "BG-12 120 mg" in black ink, is filled with enteric-coated microtablets containing dimethyl fumarate 120 mg. Nonmedicinal ingredients: microcrystalline cellulose, croscarmellose sodium, talc, colloidal silicon dioxide, magnesium stearate, triethyl citrate, methacrylic acid copolymer (type A), methacrylic acid copolymer dispersion, simethicone, sodium lauryl sulfate, and polysorbate 80. The capsule shell contains gelatin, titanium dioxide, FD&C Blue 1, yellow iron oxide, and black iron oxide.
Who should NOT take this medication?
Do not take this medication if you are allergic to dimethyl fumarate or any ingredients of the medication.