In this drug factsheet:DIN (Drug Identification Number)
|02343541 ||PROLIA 60MG/ML SOLUTION (PREFILLED SYRINGE)|
How does this medication work? What will it do for me?
Denosumab belongs to a family of medications known as monoclonal antibodies. It is used to treat osteoporosis for postmenopausal women with a high risk of fracture or who have not tolerated or responded to other osteoporosis medications. Denosumab works by reducing the amount of bone your body breaks down, making your bones less likely to break.
Your doctor may have suggested this medication for conditions other than those listed in these drug information articles. As well, some forms of this medication may not be used for all of the conditions discussed here. If you have not discussed this with your doctor or are not sure why you are being given this medication, speak to your doctor. Do not stop using this medication without consulting your doctor.
Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to use this medication if their doctor has not prescribed it.
How should I use this medication?
When used to treat osteoporosis for postmenopausal women, the recommended dose of denosumab is 60 mg injected once every 6 months. This medication is injected subcutaneously (under the skin) of the upper arm, upper thigh, or abdomen. Your doctor may show you how to give yourself the injections, or a health care professional will inject the medication for you.
Many things can affect the dose of a medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are using the medication without consulting your doctor.
It is very important to use this medication exactly as recommended by your doctor. If you miss an appointment to receive denosumab, contact your doctor as soon as possible to reschedule your appointment. If you are injecting this medication yourself and miss a dose, use it as soon as you remember. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.
This medication is stored in the refrigerator, protected from light and temperatures above 25°C, and kept out of the reach of children. It should not be allowed to freeze. It can also be stored at room temperature for 30 days. It should be allowed to reach room temperature before injecting.
Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.
What form(s) does this medication come in?
Each 1 mL single use prefilled syringe of sterile, preservative-free, clear, colourless to slightly yellow solution contains 60 mg denosumab. Nonmedicinal ingredients: sorbitol, acetate, polysorbate 20, water for injection (USP), and sodium hydroxide to adjust for pH.
Who should NOT take this medication?
Denosumab should not be used by anyone who:
- is allergic to denosumab or to any of the ingredients of the medication
- has low blood calcium levels