Brand Name
HP-Pac
Common Name
lansoprazole - clarithromcyin - amoxicillin
In this drug factsheet:
DIN (Drug Identification Number)How does this medication work? What will it do for me?
This is a product that contains three separate medications: lansoprazole, clarithromycin, and amoxicillin. Lansoprazole belongs to the group of medications called proton pump inhibitors (PPIs). Clarithromycin and amoxicillin belong to the group of medications called antibiotics. Together these medications are used to treat H. pylori (bacteria that cause inflammation in the stomach) for people with a duodenal ulcer (an ulcer at the beginning of the small intestine).
These medications are also used to reduce the risk of another duodenal ulcer occurring for people who have recently had a duodenal ulcer and who have tested positive for H. pylori. Lansoprazole helps to lower the acidity of the stomach, which helps the antibiotics (clarithromycin and amoxicillin) kill the bacteria and to heal the ulcer.
This medication may be available under multiple brand names and/or in several different forms. Any specific brand name of this medication may not be available in all of the forms or approved for all of the conditions discussed here. As well, some forms of this medication may not be used for all of the conditions discussed here.
Your doctor may have suggested this medication for conditions other than those listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are taking this medication, speak to your doctor. Do not stop taking this medication without consulting your doctor.
Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take this medication if their doctor has not prescribed it.
How should I use this medication?
The usual adult dose of this combination of medications is 30 mg of lansoprazole, 500 mg of clarithromycin and 1 g (two 500 mg capsules) of amoxicillin, twice a day before meals for 7, 10, or 14 days.
Lansoprazole capsules should be swallowed whole with water – do not crush or chew them.
Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.
It is important to take this medication exactly as prescribed by your doctor and to finish all this medication. Not doing so may decrease the effectiveness of this medication and may increase the chances of bacteria developing resistance to amoxicillin and clarithromycin.
If you miss a dose, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.
Store this medication at room temperature, protect it from light and moisture, and keep it out of the reach of children.
Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.
What form(s) does this medication come in?
Each triple therapy HP-PAC (lansoprazole - clarithromycin - amoxicillin) daily administration blister pack contains:
Lansoprazole 30 mg
Each opaque, hard gelatin, pink and black, delayed-release capsule, with the TAP logo and "PREVACID 30" imprinted on the capsule, contains lansoprazole 30 mg. Nonmedicinal ingredients: cellulosic polymers, colloidal silicon dioxide, D&C Red No. 28, FD&C Blue No. 1, FD&C Red No. 40, gelatin, magnesium carbonate, methacrylic acid copolymer, polyethylene glycol, polysorbate 80, starch, sucrose, sugar spheres, talc, and titanium dioxide.
Clarithromycin 500 mg
Each pale yellow, oval, film-coated tablet, with the Abbott logo printed on one side, contains clarithromycin 500 mg. Nonmedicinal ingredients: cellulosic polymers, croscarmellose sodium, D&C Yellow No. 10, magnesium stearate, povidone, propylene glycol, silicon dioxide, sorbic acid, sorbitan monooleate, stearic acid, talc, titanium dioxide, and vanillin. Tartrazine-free.
Amoxicillin 500 mg
Each opaque, scarlet and yellow capsule, with the Abbott logo and "500" imprinted on the capsule, contains amoxicillin trihydrate 500 mg. Nonmedicinal ingredients: colloidal silicon dioxide, D&C Yellow No. 10, dry-flo starch, FD&C Blue No. 1, FD&C Red No. 3, FD&C Red No. 40, FD&C Yellow No. 6, gelatin, magnesium stearate, sodium lauryl sulfate, talc, and titanium dioxide. Gluten- and tartrazine-free.
Who should NOT take this medication?
Do not take this medication if you:
- are allergic to lansoprazole, clarithromycin, amoxicillin, or any ingredients of these medications
- are allergic to other penicillins (e.g., cloxacillin, penicillin), cephalosporins, or other macrolide antibiotics (e.g., erythromycin, azithromycin)
- are taking astemizole, terfenadine, cisapride, pimozide, ergotamine, or dihydroergotamine
- have or may have mononucleosis
