In this drug factsheet:DIN (Drug Identification Number)
|02330989 ||MULTAQ 400MG TABLET|
How does this medication work? What will it do for me?
Dronedarone belongs to the class of medications called antiarrhythmics. It is used to help control an abnormal heart rate and rhythm called atrial fibrillation and can lower the risk of having to go the hospital for heart problems or the risk of death. It works by affecting how electrical impulses affect the heart muscle.
Your doctor may have suggested this medication for conditions other than those listed in these drug information articles. As well, some forms of this medication may not be used for all of the conditions discussed here. If you have not discussed this with your doctor or are not sure why you are taking this medication, speak to your doctor. Do not stop taking this medication without consulting your doctor.
Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take this medication if their doctor has not prescribed it.
How should I use this medication?
The usual recommended dose of this medication for adults is 400 mg twice daily with the morning and evening meal. People taking this medication should avoid drinking grapefruit juice or eating grapefruit, as this can increase the blood levels of this medication and lead to side effects and other problems.
Many things can affect the dose of a medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.
It is important that this medication be taken exactly as prescribed by your doctor. If you miss a dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.
Store this medication at room temperature in its original package and keep it out of the reach of children.
Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.
What form(s) does this medication come in?
Each white film-coated tablet for oral administration, oblong-shaped, engraved with a double wave marking on one side and "4142" code on the other side contains dronedarone hydrochloride equivalent to dronedarone 400 mg. Nonmedicinal ingredients: colloidal anhydrous silica, crospovidone, hypromellose, lactose monohydrate, magnesium stearate, maize starch, and poloxamer 407; coating: carnauba wax, hypromellose, macrogol 6000, and titanium dioxide.
Who should NOT take this medication?
Dronedarone should not be taken by anyone who:
- is allergic to dronedarone or to any of the ingredients of the medication
- is pregnant or breast-feeding
- is taking medications such as ketoconazole, itraconazole, voriconazole, cyclosporin, telithromycin, clarithromycin, nefazodone, and ritonavir
- is taking medications that can cause a change in heart rhythm called torsades de pointes (e.g., phenothiazines (promethazine, chlorpromazine), tricyclic antidepressants (amitriptyline, clomipramine, desipramine), flecainide, propafenone, quinidine, disopyramide, sotalol, amiodarone)
- has a heart rate less than 50 beats per minute
- has a type of atrial fibrillation called permanent atrial fibrillation (where a decision has been made by the doctor to not try to change the heart rhythm back to normal)
- has an electrocardiogram (ECG) that shows a problem with the electrical activity of the heart called QT prolongation
- has second or third degree heart block or sick sinus syndrome (except if treated with a pacemaker)
- has severe congestive heart failure (CHF) or other conditions associated with unstable heart function
- has severely reduced liver function