Brand Name
Erbitux
Common Name
cetuximab
In this drug factsheet:
DIN (Drug Identification Number)| 02271249 | ERBITUX 2MG/ML INJECTION |
How does this medication work? What will it do for me?
Cetuximab belongs to a group of medications called antineoplastics, or anticancer medications. It is used alone or in combination with another anticancer medication, irinotecan, to treat a certain type of colorectal cancer that has spread to other parts of the body (metastatic colorectal cancer) that has not responded to other specific anticancer medications.
It is also used along with radiation therapy to treat a certain skin cancer (squamous cell carcinoma) located on the head or neck. Cetuximab is a monoclonal antibody that recognizes and attaches to certain types of cancer cells. This may prevent cancer cells from growing and dividing.
Your doctor may have suggested this medication for conditions other than those listed in these drug information articles. As well, some forms of this medication may not be used for all of the conditions discussed here. If you have not discussed this with your doctor or are not sure why you are using this medication, speak to your doctor. Do not stop using this medication without consulting your doctor.
How should I use this medication?
The usual recommended first dose of cetuximab is 400 mg/m², given as an infusion into a vein over 2 hours. After the first dose, the usual recommended dose is 250 mg/m² every week, given over 60 minutes. Your doctor may adjust your dose based on how you respond and tolerate the medication. You doctor may prescribe other medications (e.g., diphenhydramine) to help prevent some side effects associated with the infusion.
Many things can affect the dose of a medication that a person needs, such as body weight, other medical conditions, and other medications.
This medication is usually given in an outpatient clinic, by medical staff who are familiar with treating cancer. It is important to receive this medication weekly, unless your dose is adjusted because of side effects. If you miss an appointment to receive cetuximab, contact your doctor as soon as possible to reschedule your appointment.
Before this medication is mixed, it is stored in the refrigerator and is not allowed to freeze. After mixing, it can be stored for up to 12 hours in the refrigerator and up to 8 hours at room temperature.
Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.
What form(s) does this medication come in?
Each 1 mL of clear, colourless solution contains cetuximab 2 mg. Nonmedicinal ingredients: disodium phosphate dibasic heptahydrate, sodium phosphate monobasic monohydrate, sodium chloride, sodium hydroxide, water for injection, and hydrochloric acid. Preservative-free.
Some medications may have other generic brands available. Always ask your doctor or pharmacist about the safety of switching between brands of the same medication.
Who should NOT take this medication?
Cetuximab should not be used by anyone who is allergic to cetuximab or to any of the ingredients of the medication.
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