desmopressin nasal solution
In this drug factsheet:DIN (Drug Identification Number)
|00836362 ||DDAVP SPRAY NASAL SOLUTION 10µG/METERED DOSE|
|00402516 ||DDAVP NASAL SOLUTION 0.1 MG/ML RHINYLE SOLUTION|
How does this medication work? What will it do for me?
Desmopressin nasal solution belongs to 2 classes of medications: antidiuretics and antihemorrhagics. It can be used to treat central diabetes insipidus, a condition where the kidneys are unable to conserve water due to a lack of antidiuretic hormone (ADH). This condition causes frequent urination and thirst. It is also used to treat temporary increased thirst and urination that can occur after a head injury or certain types of brain surgery. For these uses, desmopressin nasal solution works by helping to reduce the amount of urine produced by the kidneys.
Desmopressin nasal solution may also be used to prevent bleeding for people with mild hemophilia A and mild von Willebrand's disease type I. Desmopressin nasal solution works by increasing certain components involved in blood clotting.
Your doctor may have suggested this medication for conditions other than those listed in these drug information articles. As well, some forms of this medication may not be used for all of the conditions discussed here. If you have not discussed this with your doctor or are not sure why you are being given this medication, speak to your doctor. Do not stop using this medication without consulting your doctor.
Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to use this medication if their doctor has not prescribed it.
How should I use this medication?
For diabetes insipidus: The usual recommended dose for adults is 10 µg to 40 µg daily. The usual recommended dose for children 3 months to 12 years of age is 5 µg to 30 µg daily. The dose may be given as a single dose or divided into 2 or 3 doses. The lowest effective dosage should be used. Do not drink any fluids for at least 1 hour before taking desmopressin and for 8 hours after using desmopressin.
For preventing bleeding: The usual recommended dose is one 150 µg spray in each nostril, or one 150 µg spray in one nostril for people who weigh less than 50 kg (110 lbs). If it is being used to prevent bleeding related to surgery, it is given 2 hours before surgery.
Follow the instructions in the package insert on how to use medication. This medication should not be sniffed or inhaled; it works by being absorbed through the nose. To ensure the best absorption of the medication, place a finger on the outside of the nostril you just sprayed to close it for 10 seconds. During this time, breathe through the unsprayed nostril or through your mouth. If you are unsure of how to administer the medication, talk to your pharmacist.
Many things can affect the dose of a medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are using the medication without consulting your doctor.
It is important to use this medication exactly as prescribed by your doctor. If you miss a dose, administer it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not administer a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.
This medication comes in 2 forms: the spray and the rhinyle solution. Store the spray in an upright position at room temperature, protect it from light, and kept it out of the reach of children. Store the rhinyle solution in the refrigerator at 2°C to 8°C and keep it out of the reach of children.
This medication is available under multiple brand names and/or in several different forms. Any specific brand name of this medication may not be available in all of the forms listed here. The forms available for the specific brand you have searched are listed under "What form(s) does this medication come in?"
Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.
What form(s) does this medication come in?
Each mL contains desmopressin acetate 0.1 mg in an isotonic, aqueous solution containing 0.5% chlorobutanol as a preservative. Nonmedicinal incredients: sodium chloride and hydrochloric acid.
Each precompression metered dose spray pump contains desmopressin acetate 0.1 mg/mL in a buffered, isotonic, aqueous solution. Nonmedicinal ingredients: citric acid monohydrate, disodium hydrogen phosphate dehydrate, and benzalkonium chloride. Each depression delivers desmopressin acetate 10 µg.
Who should NOT take this medication?
Desmopressin nasal solution should not be used by anyone who:
- is allergic to desmopressin or to any of the ingredients of the medication
- is known to have decreased levels of sodium in their blood
- has habitual or psychogenic polydipsia (drinking excessive amounts water)
- has medical conditions that require treatment with diuretics (e.g., heart failure, high blood pressure)
- has moderately or severely reduced kidney function
- has primary nocturnal enuresis (bedwetting)
- has type IIB or platelet type (pseudo) von Willebrand's disease