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Drug Info > T > Trelstar
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DIN (Drug Identification Number)


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Brand Name

Trelstar

Common Name
triptorelin


In this drug factsheet:



DIN (Drug Identification Number)

02240000 TRELSTAR 3.75MG VIAL
02243856 TRELSTAR LA 11.25MG VIAL

How does this medication work? What will it do for me?

Triptorelin is a medication that has been designed to mimic the actions of gonadotropin releasing hormone (GnRH or luteinizing hormone releasing hormone, LHRH), the hormone released from the hypothalamus gland in the brain.

The hypothalamus uses GnRH to send messages to the pituitary gland in the brain, which then sends messages to the ovaries in women, and the testicles in men, telling these organs to produce the sex hormones estrogen (in women) and testosterone (in men).

Normally, GnRH comes from the hypothalamus in pulses, leading to the production of estrogen or testosterone. If GnRH came from the hypothalamus all of the time (rather than in "pulses"), it would have the opposite effect, and "turn off" hormone production. This is what triptorelin does.

Triptorelin is used to treat advanced prostate cancer. It reduces the amount of testosterone in the blood, which can cause the prostate cancer to grow.

When given to women, triptorelin reduces the amount of estrogen the body produces. It is used to manage and relieve chronic pain related to endometriosis because reduced levels of estrogen help to relieve the symptoms of this condition.

Your doctor may have suggested this medication for conditions other than those listed in these drug information articles. As well, some forms of this medication may not be used for all of the conditions discussed here. If you have not discussed this with your doctor or are not sure why you are taking this medication, speak to your doctor. Do not stop taking this medication without consulting your doctor.

Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take this medication if their doctor has not prescribed it.

How should I use this medication?

Triptorelin is given as an injection into the muscle by your doctor. When used to treat advanced prostate cancer, it may be given once every 28 days or once every 3 months (depending on the dosage form used). When used to treat endometriosis, it is given once every 28 days for no longer than 6 months.

Many things can affect the dose and schedule of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose or schedule different from the ones listed here, do not change the way that you are using the medication without consulting your doctor.

It is important to use this medication exactly as prescribed by your doctor. Keeping a consistent schedule of injections is important. If you miss an appointment for an injection, contact your doctor for instructions.

Triptorelin vials or dose delivery systems should be stored at room temperature and protected from light and freezing. Keep it out of the reach of children.

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.





What form(s) does this medication come in?

Trelstar (1 month slow release) 3.75 mg triptorelin per vial

Each vial of sterile lyophilized microgranules contains triptorelin pamoate which is equivalent to triptorelin peptide base 3.75 mg. Nonmedicinal ingredients: poly-d,l-lactide-co-glycolide (170 mg), mannitol, USP (85 mg), carboxymethylcellulose sodium, USP (30 mg), and polysorbate 80 USP (2 mg). When 2 mL Sterile Water for Injection is added to the microgranules and mixed, a suspension is formed, which is intended as a single, monthly intramuscular injection.

Trelstar LA (3 month slow release) 11.25 mg triptorelin/vial

Each vial of sterile lyophilized microgranules contains triptorelin pamoate which are equivalent to triptorelin peptide base 11.25 mg. Nonmedicinal ingredients: poly-d,l-lactide-co-glycolide (145 mg), mannitol, USP (85 mg), carboxymethylcellulose sodium, USP (30 mg), and polysorbate 80 USP (2 mg). When 2 mL Sterile Water for Injection is added to the microgranules and mixed, a suspension is formed, which is intended as a single, 3 month intramuscular injection.

Who should NOT take this medication?

Do not use this medication if you:

  • are allergic to triptorelin or any ingredients of this medication
  • are allergic to medications called GnRH agonists or LHRH agonists (such as buserelin or goserelin)
  • are breast-feeding
  • are pregnant or may become pregnant while taking this medication
  • have vaginal bleeding of unknown cause


 

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