alendronate - cholecalciferol
In this drug factsheet:DIN (Drug Identification Number)
|02276429 ||FOSAVANCE 70MG/2800UNIT TABLET|
|02314940 ||FOSAVANCE 70MG/5600UNIT TABLET|
How does this medication work? What will it do for me?
This is a combination medication that contains alendronate and cholecalciferol. It is used to treat osteoporosis for postmenopausal women and for men. Alendronate belongs to a family of medications known as bisphosphonates.
Alendronate increases the thickness of bone (bone mineral density) by slowing down the cells that usually break down bone (osteoclasts). This allows the cells that build bone (osteoblasts) to work more efficiently. By making bones stronger, alendronate can help to reduce the incidence of osteoporosis-related fractures.
Cholecalciferol, also called vitamin D3, is a vitamin that is needed for calcium absorption and healthy bones.
This medication may be available under multiple brand names and/or in several different forms. Any specific brand name of this medication may not be available in all of the forms or approved for all of the conditions discussed here. As well, some forms of this medication may not be used for all of the conditions discussed here.
Your doctor may have suggested this medication for conditions other than those listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are taking this medication, speak to your doctor. Do not stop taking this medication without consulting your doctor.
Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take this medication if their doctor has not prescribed it.
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How should I use this medication?
The recommended dose of alendronate - cholecalciferol is one tablet once weekly. The overall appropriate dosage of alendronate - cholecalciferol for you is determined by your doctor and is based on how much vitamin D you require.
The tablet should be taken first thing in the morning when you get up, and at least half an hour before you take your first meal, beverage, or other medication of the day. To reduce the risk of irritating the throat or esophagus, take the tablet with a full glass (250 mL) of plain water only. If your normal drinking water is classified as "hard water," it may decrease the absorption of this medication and you should consider taking it with distilled water.
After swallowing, do not lie down until 30 minutes have passed and you have eaten your first meal of the day. Do not take this medication at bedtime or before getting up in the morning. Swallow the tablets whole. Do not chew or suck on the tablets.
Many things can affect the dose of medication that a person needs, such as the severity of the condition, other medical conditions and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.
It is important to take this medication exactly as prescribed by your doctor. If you miss a dose, take the missed dose the morning after you remember. Then, return to your weekly dose on the original day of the week. Do not take 2 doses on the same day or take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.
Store this medication at room temperature, protect it from light and moisture, and keep it out of the reach of children. Store the tablets in the original blister package until use.
Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.
What form(s) does this medication come in?
70 mg/2,800 IU
Each white-to-off-white, modified capsule-shaped tablet, with code "710" on one side and an outline of a bone image on the other, contains alendronate monosodium salt trihydrate 91.37 mg, the molar equivalent of 70 mg of alendronate and cholecalciferol 70 µg equivalent to 2,800 IU vitamin D. Nonmedicinal ingredients: butylated hydroxytoluene, colloidal silicon dioxide, croscarmellose sodium, gelatin, lactose anhydrous, magnesium stearate, medium chain triglycerides, microcrystalline cellulose, modified food starch (corn), sodium aluminum silicate, and sucrose. Gluten-free.
70 mg/5,600 IU
Each white to off-white, modified rectangle-shaped tablet, with code "270" on one side and an outline of a bone image on the other, contains alendronate monosodium salt trihydrate 91.37 mg, the molar equivalent of 70 mg of free acid and cholecalciferol 140 µg equivalent to 5,600 IU vitamin D. Nonmedicinal ingredients: butylated hydroxytoluene, colloidal silicon dioxide, croscarmellose sodium, gelatin, lactose anhydrous, magnesium stearate, medium chain triglycerides, microcrystalline cellulose, modified food starch (corn), sodium aluminum silicate, and sucrose. Gluten-free.
Who should NOT take this medication?
Do not take alendronate - cholecalciferol if you:
- are allergic to alendronate, cholecalciferol, or any ingredients of the medication
- cannot stand or sit upright for at least 30 minutes
- have an abnormality of the esophagus (passage leading from throat to stomach) that delays the emptying of the esophagus into the stomach
- have low blood calcium
- have reduced kidney function (creatinine clearance less than 35 mL per minute)