In this drug factsheet:
How does this medication work? What will it do for me?
Ramipril belongs to the class of medications called angiotensin-converting enzyme (ACE) inhibitors. It is used alone and in combination with specific diuretics (water pills) to treat high blood pressure. Ramipril may also be used to reduce the risk of problems associated with heart disease (e.g., heart attack, stroke, or death) for people over 55 years old who are at a high risk of having these problems.
It is also given to certain people after heart attacks to improve survival and reduce the risk of hospitalization for heart failure. It works by relaxing blood vessels and by making the heart pump more efficiently.
This medication may be available under multiple brand names and/or in several different forms. Any specific brand name of this medication may not be available in all of the forms or approved for all of the conditions discussed here. As well, some forms of this medication may not be used for all of the conditions discussed here.
Your doctor may have suggested this medication for conditions other than those listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are taking this medication, speak to your doctor. Do not stop taking this medication without consulting your doctor.
Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take this medication if their doctor has not prescribed it.
People who read this article also read about:
How should I use this medication?
The recommended adult dose of ramipril ranges from 2.5 mg to 10 mg daily in 1 or 2 divided doses, depending on the dose and circumstances. The maximum daily dose of this medication is 20 mg.
To treat high blood pressure, the usual starting dose for people not using diuretics (water pills) is 2.5 mg once daily. The dose is usually increased according to need every 2 weeks. The usual dose range is between 2.5 mg and 10 mg daily. For people using diuretics, your doctor may start with a lower dose of 1.25 mg daily or ask you to stop using the diuretic for 2 or 3 days before starting ramipril.
For people at increased risk of heart disease events, the recommended starting dose is 2.5 mg once daily, increasing gradually to 10 mg daily if tolerated.
For treatment following a heart attack, the usual starting dose varies depending on existing medical conditions, blood pressure, and other medications. The recommended starting dose is 2.5 mg twice daily, increased every 1 to 3 days if appropriate. The dose should not exceed 5 mg twice daily. A lower dose of 1.25 mg twice daily may be needed for those who experience low blood pressure as a result of taking the medication.
Many things can affect the dose of a medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.
It is important that this medication be taken exactly as prescribed by your doctor. If you miss a dose, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.
Store this medication at room temperature and keep it out of the reach of children.
Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.
What form(s) does this medication come in?
ratio-Ramipril is no longer being manufactured for sale in Canada. For brands that may still be available, search under ramipril. This article is being kept available for reference purposes only. If you are using this medication, speak with your doctor or pharmacist for information about your treatment options.
Who should NOT take this medication?
Do not take ramipril if you:
- are allergic to ramipril, or any other ACE inhibitor, or any ingredients of the medication
- are breast-feeding
- are pregnant
- have had angioedema (a serious allergic reaction which causes the area around the throat and tongue to swell)
- have low blood pressure
- have narrowing of the blood vessels to the kidneys