In this drug factsheet:DIN (Drug Identification Number)
|00899356 ||MANERIX 150MG TABLET|
|02166747 ||MANERIX 300MG TABLET|
How does this medication work? What will it do for me?
Moclobemide belongs to the class of antidepressants known as monoamine oxidase (MAO) inhibitors. It is used to treat depression. Depression is believed to be caused by imbalances in certain brain chemicals. This medication works by bringing these chemicals back into balance.
This medication may be available under multiple brand names and/or in several different forms. Any specific brand name of this medication may not be available in all of the forms or approved for all of the conditions discussed here. As well, some forms of this medication may not be used for all of the conditions discussed here.
Your doctor may have suggested this medication for conditions other than those listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are taking this medication, speak to your doctor. Do not stop taking this medication without consulting your doctor.
Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take this medication if their doctor has not prescribed it.
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How should I use this medication?
The usual starting dose of moclobemide for adults is 150 mg twice daily. If necessary, your doctor may gradually increase your dose after the first week to a maximum of 300 mg twice daily. The recommended dose of moclobemide for adults ranges from 150 mg to 300 mg, taken twice daily after meals.
Moclobemide should be swallowed whole with a glass of water. Do not split, crush, chew, or dissolve the tablets.
This medication may take a few days to several weeks to achieve the best effect. Unlike other MAO inhibitors, no special dietary restrictions are necessary when taking moclobemide. It is very important, however, to always take this medication immediately after you have eaten.
Many things can affect the dose of a medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.
It is important to take this medication exactly as prescribed by your doctor. Do not stop taking this medication without talking to your doctor first, even if you start to feel better. If you miss a dose, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.
Store this medication at room temperature and keep it out of the reach of children.
Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.
What form(s) does this medication come in?
Each pale yellow, single-scored, biconvex, film-coated tablet contains 150 mg of moclobemide. Nonmedicinal ingredients: cornstarch, ethylcellulose, iron oxide, lactose, magnesium stearate, methylhydroxypropyl cellulose, polyethylene glycol, povidone, sodium starch glycolate, talc, and titanium dioxide.
Each white, single-scored, biconvex, film-coated tablet contains 300 mg of moclobemide. Nonmedicinal ingredients: cornstarch, ethylcellulose, lactose, magnesium stearate, methylhydroxypropyl cellulose, polyethylene glycol, povidone, sodium starch glycolate, talc, and titanium dioxide.
Who should NOT take this medication?
Do not take this medication if you:
- are allergic to moclobemide or any ingredients of the medication
- are in an acute state of confusion
- are are taking any of the following medications:
- other MAO inhibitors (e.g., tranylcypromine)
- SNRI antidepressants (e.g., desvenlafaxine)
- SSRI antidepressants (e.g., fluoxetine, sertraline)
- tricyclic antidepressants (e.g., amitriptyline)
- “triptan” migraine medications (e.g., sumatriptan)