bupropion (smoking cessation)
In this drug factsheet:DIN (Drug Identification Number)
|02238441 ||ZYBAN 150MG SR TABLET|
How does this medication work? What will it do for me?
Bupropion belongs to the family of medications known as antidepressants
. It is used in addition to counselling, as an aid for quitting smoking.
It may also be used with nicotine replacement products. In general, nicotine replacement therapy alone should be tried before using bupropion. Bupropion works by affecting the balance of chemicals that occur naturally in the brain. This helps reduce withdrawal symptoms and the urge to smoke.
This medication may be available under multiple brand names and/or in several different forms. Any specific brand name of this medication may not be available in all of the forms or approved for all of the conditions discussed here. As well, some forms of this medication may not be used for all of the conditions discussed here.
Your doctor may have suggested this medication for conditions other than those listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are taking this medication, speak to your doctor. Do not stop taking this medication without consulting your doctor.
Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take this medication if their doctor has not prescribed it.
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How should I use this medication?
The recommended dose as an aid for smoking cessation is 150 mg daily for 3 days, followed by 150 mg twice daily. You should start taking bupropion at least one week before stopping smoking.
Multiple daily doses should be taken at least 8 hours apart. It is very important that bupropion tablets be swallowed whole and not chewed, broken, or crushed. Bupropion may be taken with food or on an empty stomach.
Many things can affect the dose of a medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.
It is important that this medication be taken exactly as prescribed by your doctor. If you miss a dose of this skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.
Store this medication at room temperature, protect it from light and moisture, and keep it out of the reach of children.
Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.
What form(s) does this medication come in?
Each purple, round, biconvex, film-coated, sustained-release tablet, printed "ZYBAN 150", contains bupropion HCl 150 mg. Nonmedicinal ingredients: carnauba wax, cysteine hydrochloride, edible black ink, FD&C Blue No. 2 Lake, FD&C Red No. 40 Lake, hydroxypropyl methylcellulose, magnesium stearate, microcrystalline cellulose, polyethylene glycol, polysorbate 80, and titanium dioxide.
Who should NOT take this medication?
Do not take this medication if you:
- are allergic to bupropion or to any of the ingredients of this medication
- are currently taking thioridazine (an antipsychotic medication) or have taken it in the past 2 weeks
- are having abrupt withdrawal issues from alcohol, benzodiazepines (e.g., diazepam, clonazepam, lorazepam), or other sedatives (e.g., phenobarbital)
- are taking another medication that contains bupropion (e.g., Wellbutrin XL® or Wellbutrin® SR)
- have a seizure disorder
- have or have had an eating disorder (bulimia or anorexia nervosa)
- have taken a monoamine oxidase inhibitor (MAO inhibitor; e.g., phenelzine, tranylcypromine) within the past 2 weeks