In this drug factsheet:DIN (Drug Identification Number)
|02299437 ||OCTREOTIDE 100µG/ML INJECTION|
|02299445 ||OCTREOTIDE 200µG/ML INJECTION|
|02299453 ||OCTREOTIDE 500µG/ML INJECTION|
How does this medication work? What will it do for me?
Octreotide is a man-made (synthetic) version of a naturally occurring hormone known as somatostatin. Octreotide is used to treat severe diarrhea, flushing, and other symptoms that occur with certain cancers of the intestine. It works by slowing down the release of substances that cause diarrhea and flushing and by increasing water absorption.
Octreotide also reduces the amount of growth hormone in the body, and so it is also used to treat acromegaly, a condition associated with overgrowth of the hands, feet, and parts of the face.
Octreotide is also used for emergency treatment of certain causes of bleeding in the esophagus and stomach, and to prevent complications after pancreas surgery.
Your doctor may have suggested this medication for conditions other than those listed in these drug information articles. As well, some forms of this medication may not be used for all of the conditions discussed here. If you have not discussed this with your doctor or are not sure why you are being given this medication, speak to your doctor. Do not stop using this medication without consulting your doctor.
Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to use this medication if their doctor has not prescribed it.
How should I use this medication?
The recommended dose and dosing schedule of octreotide varies according to the specific condition being treated, the response to therapy, and the other medications or treatments being used. Short-acting octreotide is injected under the skin (subcutaneous) of the hip, thigh, or abdomen 2 to 4 times daily. Long-lasting octreotide is injected by a health care professional into the gluteal muscle (the buttocks) every 4 weeks. When used to treat bleeding in the esophagus and stomach, octreotide is given intravenously (into a vein).
Many things can affect the dose of a medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are using the medication without consulting your doctor.
If you are giving yourself injections, it is important to use this medication exactly as prescribed by your doctor and to follow the instructions included with the medication very carefully. Do not use this medication if it is discoloured or there are particles floating in it.
If you miss a dose of the short-acting medication, use it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not inject a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.
It is important that the long-acting form of this medication be given exactly as recommended by your doctor. If you miss an appointment to receive octreotide, contact your doctor as soon as possible to reschedule your appointment.
Octreotide can cause a number of side effects. Your doctor, nurse, or pharmacist can advise you on how to reduce the effects of nausea and vomiting. Keep track of any side effects and report them to your doctor, as suggested in the section "What side effects are possible with this medication?"
For prolonged storage, the short-acting form of this medication is stored in the refrigerator in its original carton (to protect it from light) and kept out of the reach of children. For day-to-day use, store this medication at room temperature for up to 2 weeks and protect it from light.
The long-acting form of this medication is stored in the refrigerator in its original carton (to protect it from light) but can be kept at room temperature on the day it is injected.
This medication is available under multiple brand names and/or in several different forms. Any specific brand name of this medication may not be available in all of the forms listed here. The forms available for the specific brand you have searched are listed under "What form(s) does this medication come in?"
Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.
What form(s) does this medication come in?
Each mL contains 100 µg or 500 µg of octreotide as acetate. Nonmedicinal ingredients: glacial acetic acid, sodium acetate trihydrate, mannitol, and water for injection.
Each multidose vial contains octreotide as acetate 1,000 µg (200 µg/mL). Nonmedicinal ingredients: glacial acetic acid, sodium acetate trihydrate, mannitol, phenol, and water for injection.
Who should NOT take this medication?
Octreotide should not be used by anyone who is allergic to octreotide or to any of the ingredients of the medication.