In this drug factsheet:DIN (Drug Identification Number)
|02301482 ||CYMBALTA 30MG CAPSULE|
|02301490 ||CYMBALTA 60MG CAPSULE|
How does this medication work? What will it do for me?
Duloxetine belongs to the class of medications called selective serotonin and norepinephrine reuptake inhibitors (SSNRIs). It is used to treat depression and generalized anxiety disorder. It can also be used to treat diabetes-related nerve pain, fibromyalgia, chronic low back pain, and chronic pain from osteoarthritis of the knee.
For depression and anxiety, duloxetine works by affecting the balance of chemicals in the brain and other parts of the body. For certain types of pain, duloxetine works by affecting the balance of chemicals in the brain and spinal cord that are involved in the experience of pain.
This medication may be available under multiple brand names and/or in several different forms. Any specific brand name of this medication may not be available in all of the forms or approved for all of the conditions discussed here. As well, some forms of this medication may not be used for all of the conditions discussed here.
Your doctor may have suggested this medication for conditions other than those listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are taking this medication, speak to your doctor. Do not stop taking this medication without consulting your doctor.
Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take this medication if their doctor has not prescribed it.
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How should I use this medication?
The usual recommended dose is 60 mg once daily. Some people may start on a lower dose of 30 mg once daily. It usually starts to work within 1 to 4 weeks for depression and anxiety and within the first week of treatment for diabetes-related nerve pain, fibromyalgia, chronic back pain, and chronic osteoarthritis knee pain.
Duloxetine should be taken at the same time each day. It can be taken with or without food, but taking it with food may help to reduce nausea that may occur at the start of treatment.
Swallow capsules whole. Do not crush or chew the capsules, and do not sprinkle the contents of the capsule into foods or liquids.
Many things can affect the dose of a medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.
It is important to take this medication exactly as prescribed by your doctor. If you miss a dose by a few hours, take it as soon as you remember and continue with your regular schedule. If most of the day has passed, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.
Store this medication at room temperature, protect it from light and moisture, and keep it out of the reach of children.
Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.
What form(s) does this medication come in?
Each opaque white body and opaque blue cap, delayed-release capsule, imprinted "30 mg" on the body and "9543" on the cap, contains duloxetine 30 mg. Nonmedicinal ingredients: FD&C Blue No. 2, gelatin, hydroxypropyl methylcellulose, hydroxypropyl methylcellulose acetate succinate, sodium lauryl sulfate, sucrose, sugar spheres, talc, titanium dioxide, and triethyl citrate.
Each opaque green body and opaque blue cap, delayed-release capsule, imprinted "60 mg" on the body and "9542" on the cap, contains duloxetine 60 mg. Nonmedicinal ingredients: FD&C Blue No. 2, gelatin, hydroxypropyl methylcellulose, hydroxypropyl methylcellulose acetate succinate, sodium lauryl sulfate, sucrose, sugar spheres, talc, titanium dioxide, triethyl citrate, and yellow iron oxide.
Who should NOT take this medication?
Do not take this medication if you:
- are allergic to duloxetine or to any of the ingredients of the medication
- have liver disease causing reduced liver function
- have severely reduced kidney function
- have uncontrolled narrow-angle glaucoma
- are taking fluvoxamine and other medications with a similar effect on drug metabolism in the liver (check with your pharmacist)
- are taking MAO inhibitors (e.g., phenelzine, tranylcypromine, linezolid, methylene blue) or have taken a MAO inhibitor within 2 weeks of starting duloxetine
- are taking quinolone medications (e.g., ciprofloxacin, norfloxacin)
- are taking thioridazine