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Drug Info > A > Apo-Risedronate
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DIN (Drug Identification Number)


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Brand Name

Apo-Risedronate

Common Name
risedronate


In this drug factsheet:



DIN (Drug Identification Number)

02353687 APO-RISEDRONATE 35MG TABLET

How does this medication work? What will it do for me?

Risedronate belongs to a group of medications called bisphosphonates. It is used to treat and prevent osteoporosis for women who are past menopause and to treat and prevent osteoporosis caused by treatment with corticosteroids (e.g., prednisone) for men and women. It is also used to improve bone mineral density for men with osteoporosis, and to treat a condition called Paget's disease. The long-acting form of risedronate is used to treat osteoporosis in women who are past menopause only.

Risedronate increases the thickness of bone (bone mineral density) by slowing down the cells that usually break down bone (osteoclasts). This allows the cells that build bone (osteoblasts) to work more efficiently. By making bones stronger, risedronate can help to reduce the incidence of osteoporosis-related fractures.

This medication may be available under multiple brand names and/or in several different forms. Any specific brand name of this medication may not be available in all of the forms or approved for all of the conditions discussed here. As well, some forms of this medication may not be used for all of the conditions discussed here.

Your doctor may have suggested this medication for conditions other than those listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are taking this medication, speak to your doctor. Do not stop taking this medication without consulting your doctor.

Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take this medication if their doctor has not prescribed it.

Learn more about related conditions:

These conditions are related to the conditions the drug is approved to treat. The drug may not be approved to treat all of the conditions listed here.

How should I use this medication?

For preventing osteoporosis in women who are past menopause, the recommended dose of risedronate is 5 mg once daily or 35 mg once weekly.

For treating osteoporosis in women who are past menopause, there are multiple schedules for taking risedronate. It may be taken 5 mg once daily, 35 mg once weekly, 75 mg on 2 consecutive days per month on the same calendar days each month, or 150 mg once a month on the same calendar day each month.

For treating osteoporosis in men, the recommended dose of risedronate is 35 mg once weekly.

For treatment and prevention of osteoporosis caused by treatment with corticosteroids, the recommended dose of risedronate is 5 mg daily.

For treatment of Paget's disease, the recommended dose is 30 mg once daily for 2 months.

Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.

It is important to take this medication exactly as prescribed by your doctor.

(For all regular release forms of Risedronate)

The tablet should be taken with plain water at least 30 minutes before the first food or drink of the day. It may also be taken at least 2 hours after any food or drink other than plain water. Do not eat or drink for 2 hours before and for at least 30 minutes after taking the tablet.

(For delayed release risedronate (Actonel DR) only)

The delayed release 35 mg tablet should be taken in the morning with breakfast to reduce the likelihood of experiencing upper abdominal pain.

All strengths of risedronate should be taken while sitting in an upright position and swallowed whole (not chewed) with at least a half glass of water (i.e., at least 120 mL). Do not lie down for at least 30 minutes after taking the medication to prevent any irritation to your esophagus (the tube connecting the mouth and stomach).

If you are taking calcium supplements or aluminum-, iron-, or magnesium-containing medications (e.g., antacids and mineral supplements), you should take them at a different time of day. When taken together with risedronate, they will decrease the amount of risedronate that is delivered from your stomach into your body and reduce the effectiveness of the risedronate.

If you are taking this medication on a once-daily schedule and then miss a dose, do not take it later in the day. Resume your usual schedule the next morning. Do not take 2 doses at the same time.

If you are taking this medication on a once-weekly basis and you forget to take it on the regularly scheduled day, take one tablet on the day you first remember. Then, return to taking one tablet once a week on your regularly scheduled day. Do not take 2 tablets on the same day.

If you are taking this medication on a twice-monthly basis (schedule of 2 doses on 2 consecutive days per month) and miss a dose and the next month's scheduled doses are more than 7 days away, take the missed tablet in the morning after the day it is remembered. If both tablets are missed, take one tablet in the morning after the day it is remembered and the second tablet on the next consecutive morning. If you remember the missed dose and are within 7 days of the next month's scheduled doses, skip the missed dose(s), and wait until the next month's scheduled dose to continue.

If you are taking this medication on a once-monthly basis and miss a dose and the next month's scheduled dose is more than 7 days away, take the missed dose in the morning after the day it is remembered. If a dose is missed within 7 days of the next month's scheduled dose, skip the missed dose and wait until the next month's scheduled dose to continue.

Store this medication at room temperature, protect it from light and moisture, and keep it out of the reach of children.

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.





What form(s) does this medication come in?

35 mg
Each oval, orange, coated tablet, debossed with "RS" on one side and "35" on the other side, contains the equivalent of 35 mg of anhydrous risedronate sodium in the form of the hemi-pentahydrate with small amounts of monohydrate. Nonmedicinal ingredients: colloidal silicon dioxide, iron oxide red, iron oxide yellow, maltodexterin, mannitol, polyvinyl alcohol-polyethylene glycol graft copolymer, povidone, pregelatinized starch, sodium starch glycolate, sodium stearyl fumarate, sucrose, talc, titaniun dioxide, and triethyl citrate.

150 mg
Each light blue, oval, biconvex coated tablet, engraved "APO" on one side, "RIS150" on the other side, contains risedronate sodium hemipentahydrate equivalent to 150 mg risedronate sodium. Nonmedicinal ingredients: colloidal silicon dioxide, crospovidone, hydroxypropyl methylcellulose 2910 E5, hydroxypropyl cellulose type LF, anhydrous lactose, magnesium stearate, polyethylene glycol 8000, indigotine AL Lake 12-14% (Blue No. 2), sodium phosphate monobasic monohydrate, sodium phosphate dibasic anhydrous, and titanium dioxide.

Who should NOT take this medication?

Do not take risedronate if you:

  • are allergic to risedronate or any ingredients of this medication
  • have low levels of calcium in the blood


 

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