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Drug Info > S > Supeudol
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ABCDEFGHIJKLMNOPQRSTUVWXYZ

Brand Name
Supeudol

Common Name
oxycodone


In this drug factsheet:



What side effects are possible with this medication?

Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.

The side effects listed below are not experienced by everyone who takes this medication. If you are concerned about side effects, discuss the risks and benefits of this medication with your doctor.

The following side effects have been reported by at least 1% of people taking this medication. Many of these side effects can be managed, and some may go away on their own over time.

Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.

  • constipation
  • dizziness
  • drowsiness
  • dry mouth
  • headache
  • lack of energy or tiredness
  • nausea
  • sweating
  • vomiting

Although most of the side effects listed below don't happen very often, they could lead to serious problems if you do not check with your doctor or seek medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

  • itching
  • facial redness or flushing

Stop taking the medication and seek immediate medical attention if any of the following occur:

  • chest tightness or wheezing
  • convulsions (seizures)
  • fainting
  • rapid heartbeat
  • signs of a severe allergic reaction (hives; difficulty breathing; swelling of the face, throat, or tongue)

Seek immediate medical attention if any of the following symptoms of overdose occur:

  • blue tinge to lips
  • cold, clammy skin
  • confusion
  • dizziness
  • extreme drowsiness
  • pinpoint pupils
  • slow or troubled breathing
  • slow heartbeat

Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking this medication.

Are there any other precautions or warnings for this medication?

Before you begin using a medication, be sure to inform your doctor of any medical conditions or allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use this medication.

Abdominal (stomach) conditions: Oxycodone and other narcotic medications may make the diagnosis of abdominal conditions more difficult or it may worsen these conditions. If you have abdominal problems, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.

Alcohol: Do not consume alcohol while taking this medication, as this may lead to dangerous side effects.

Constipation: Constipation happens frequently while taking opioid (narcotic) pain relievers on a regular basis. Your doctor will discuss the use of stimulant laxatives, stool softeners, and other measures to be used as required.

Controlled-release: Controlled-release forms of this medication are designed to work over 12 hours when swallowed whole. If a tablet is broken, cut, crushed, dissolved, or chewed, the entire 12-hour dose will be absorbed rapidly into your body. This can be very dangerous, causing serious problems such as slowed breathing and overdose, which can be fatal.

Dependence and withdrawal: As with other opioid medications (narcotics), this medication may become habit-forming if taken for long periods of time. Misuse of oxycodone is usually not a problem when it is used appropriately for pain relief. Physical dependence, or tolerance (a need to take regular doses to prevent physical symptoms) has been associated with narcotic analgesics such as oxycodone. Withdrawal symptoms may be experienced if the dose is significantly reduced or suddenly discontinued. Reducing the dose gradually under medical supervision can help prevent or decrease these withdrawal symptoms when this medication is no longer required for pain control.

Withdrawal symptoms (e.g., body aches, diarrhea, nervousness, restlessness, runny nose, sneezing, goose bumps, shaking, shivering, nausea, stomach cramps, fast heart rate, fever, sweating) may occur if oxycodone is stopped suddenly. If you have been taking this medication for a long time and no longer require it for pain control, you should stop the medication gradually as directed by your doctor.

Difficulty breathing: Oxycodone can cause serious breathing problems, particularly for people having an acute asthma attack or those with chronic obstructive pulmonary disease (chronic bronchitis, emphysema) or other conditions that affect breathing. If you experience slowed breathing or difficulty breathing, seek immediate medical attention. If you have lung problems, or are taking other medications that can slow breathing, you are more at risk for experiencing this.

If you have asthma or other breathing disorders, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.

Drowsiness/reduced alertness: Oxycodone may impair the mental or physical abilities needed for activities such as driving or operating machinery. Do not drive or perform other potentially hazardous tasks if this medication affects your ability to do these safely.

Head injury: Oxycodone can cause increased pressure inside the head. If you have an acute head injury or any other condition which increases the pressure inside your head, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.

Kidney function: Kidney disease or reduced kidney function may cause this medication to build up in the body, causing side effects. If you have severely reduced kidney function, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.

Liver function: Liver disease or reduced liver function may cause this medication to build up in the body, causing side effects. If you have severely reduced liver function, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.

Medical conditions: If you have abnormal heart rhythms, reduced adrenal function (e.g., Addison's disease), low thyroid, inflammation of the pancreas, enlarged prostate, or urethral strictures, oxycodone may cause increased symptoms or your condition to become worse. Discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.

Stopping the medication: Do not suddenly stop taking this medication since withdrawal symptoms may occur. These symptoms may include body aches, diarrhea, nervousness, restlessness, runny nose, sneezing, goose bumps, shaking, shivering, nausea, stomach cramps, fast heart rate, fever, sweating, and confusion. Your doctor will advise you on how to safely stop taking this medication if you no longer require it for pain control.

Pregnancy: This medication should not be used during pregnancy. Infants born to mothers who have taken oxycodone during pregnancy have been born with signs of narcotic withdrawal. If you become pregnant while taking this medication, contact your doctor immediately.

Breast-feeding: It is not known if oxycodone passes into breast milk. If you are a breast-feeding mother and are taking this medication, it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.

Children: The safety and effectiveness of using this mediation have not been established for children. Accidental ingestion of this medication by children may lead to severe and even fatal consequences. Keep this medication out of the reach of children.

Seniors: Seniors may be more sensitive to the effects of this medication.





What other drugs could interact with this medication?

There may be an interaction between oxycodone and any of the following:

  • alcohol
  • amiodarone
  • anaesthetics
  • amphetamines (e.g.,dextroamphetamine, lisdexamphetamine)
  • antihistamines (e.g., chlorpheniramine, diphenhydramine, hydroxyzine)
  • antipsychotics (e.g., chlorpromazine, haloperidol, olanzapine, quetiapine, risperidone)
  • antiseizure medications (e.g., clobazam, ethosuximide, felbamate, levetiracetam, phenobarbital, phenytoin, primidone, topiramate, valproic acid, zonisamide)
  • aprepitant
  • atropine
  • azelastine
  • "azole" antifungals (e.g., itraconazole, ketoconazole, voriconazole)
  • barbiturates (e.g., secobarbital, phenobarbital)
  • benzodiazepines (e.g., diazepam, lorazepam)
  • benztropine
  • beta-blockers (e.g., metoprolol, propranolol)
  • bicalutamide
  • boceprevir
  • bosentan
  • brimonidine
  • calcium channel blockers (e.g., amlodipine, diltiazem, nifedipine, verapamil)
  • chloral hydrate
  • ciprofloxacin
  • cimetidine
  • conivaptan
  • cyclobenzaprine
  • cyclosporine
  • desmopressin
  • dexamethasone
  • dimenhydrinate
  • diuretics (water pills; e.g., furosemide, hydrochlorothiazide, triamterene)
  • dronabinol
  • droperidol
  • grapefruit juice
  • HIV non-nucleoside reverse transcriptase inhibitors (NNRTIs; e.g., delaviridine, efavirenz, etravirine, nevirapine)
  • HIV protease inhibitors (e.g., atazanavir, indinavir, ritonavir, saquinavir)
  • ipratropium
  • macrolide antibiotics (e.g., clarithromycin, erythromycin)
  • methotrimeprazine
  • metronidazole
  • metyrosine
  • mifepristone
  • mirtazapine
  • mitotane
  • monoamine oxidase inhibitors (MAOIs; e.g., moclobemide, phenelzine, rasagiline, selegiline, tranylcypromine)
  • nabilone
  • naltrexone
  • other narcotic pain relievers (e.g., codeine, fentanyl, hydromorphone, morphine)
  • nefazodone
  • norfloxacin
  • octreotide
  • olopatadine
  • orphenadrine
  • oxybutynin
  • pramipexole
  • procyclidine
  • rifabutin
  • rifampin
  • ropinirole
  • St. John’s wort
  • scopolamine
  • selective serotonin reuptake inhibitors (SSRIs; e.g., citalopram, duloxetine, fluoxetine, paroxetine, sertraline)
  • simeprevir
  • tapentadol
  • telaprevir
  • tetracycline
  • thalidomide
  • tiotropium
  • tramadol
  • trihexyphenidyl
  • tyrosine kinase inhibitors (e.g., dasatinib, imatinib, nilotinib, sunatinib)
  • zolpidem
  • zopiclone

If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:

  • stop taking one of the medications,
  • change one of the medications to another,
  • change how you are taking one or both of the medications, or
  • leave everything as is.

An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.

Medications other than those listed above may interact with this medication. Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.





 

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