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Drug Info > I > Imitrex DF
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DIN (Drug Identification Number)


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Brand Name

Imitrex DF

Common Name
sumatriptan


In this drug factsheet:



DIN (Drug Identification Number)

02212161 IMITREX DF 100MG TABLET
02212153 IMITREX DF 50MG TABLET

How does this medication work? What will it do for me?

Sumatriptan belongs to a class of medications known as 5-hydroxytryptamine agonists (also called "triptans"). It is used to treat migraine headaches with or without aura (warning signs that occur prior to the onset of a migraine). The pain of migraine headaches is thought to be caused by dilated blood vessels inside the head. Sumatriptan relieves migraine headaches by constricting these blood vessels.

Sumatriptan is not recommended for other types of headache or for headache prevention.

In most people, sumatriptan eliminates or reduces the symptoms of migraine, including headache, nausea, vomiting, and sensitivity to light and sound. Significant relief of migraine pain is usually experienced by about 10 to 15 minutes after using the injection, 15 minutes after using the nasal spray, and about 30 minutes after taking the oral tablets.

This medication may be available under multiple brand names and/or in several different forms. Any specific brand name of this medication may not be available in all of the forms or approved for all of the conditions discussed here. As well, some forms of this medication may not be used for all of the conditions discussed here.

Your doctor may have suggested this medication for conditions other than those listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are being given this medication, speak to your doctor. Do not stop using this medication without consulting your doctor.

Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to use this medication if their doctor has not prescribed it.

Learn more about related conditions:

These conditions are related to the conditions the drug is approved to treat. The drug may not be approved to treat all of the conditions listed here.

How should I use this medication?

The recommended adult dose of the tablets ranges from 25 mg to 100 mg. The most common dose is 50 mg.

If the headache returns, or if there is partial but not total relief, the dose may be repeated after 2 hours. If a dose has not helped your headache at all, do not take a second dose without first consulting a doctor. No more than 200 mg should be taken during any 24-hour period.

Swallow the tablet whole with water. Do not crush, chew, or split the tablets. The DF tablets have been formulated to disintegrate and release medication into the stomach so that it is absorbed into the bloodstream.

It is important to take this medication exactly as prescribed by your doctor.

Many things can affect the dose of a medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.

Store this medication at room temperature, protect it from moisture, and keep it out of the reach of children.

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.





What form(s) does this medication come in?

50 mg
Each white, film-coated tablet contains sumatriptan (base) 50 mg as the succinate salt. Nonmedicinal ingredients: croscarmellose sodium, dibasic calcium phosphate anhydrous, magnesium stearate, hydroxypropyl methylcellulose, microcrystalline cellulose, sodium bicarbonate, titanium dioxide, and triacetin. Gluten- and tartrazine-free.

100 mg
Each pink, film-coated tablet contains sumatriptan (base) 100 mg as the succinate salt. Nonmedicinal ingredients: croscarmellose sodium, dibasic calcium phosphate anhydrous, iron oxide red, magnesium stearate, hydroxypropyl methylcellulose, microcrystalline cellulose, sodium bicarbonate, titanium dioxide, and triacetin. Gluten- and tartrazine-free.

Who should NOT take this medication?

Do not use sumatriptan if you:

  • are allergic to sumatriptan or any ingredient of the medication
  • are taking monoamine oxidase (MAO) inhibitors (e.g., phenelzine, tranylcypromine) or have taken them within the past 2 weeks
  • do not have a clear diagnosis of migraine
  • have angina (chest pain), including Prinzmetal's angina (coronary vasospasm)
  • have blood vessel disease (e.g., ischemic bowel disease, Raynaud's syndrome, stroke, transient ischemic attacks [TIAs])
  • have certain types of migraine headaches (including hemiplegic, basilar, or ophthalmoplegic migraine)
  • have had a heart attack
  • have heart disease (e.g., heart valve disease, ischemic heart disease, abnormal heart rhythms, congenital heart disease)
  • have high blood pressure that is severe or not under control
  • have severely reduced liver function
  • have taken another 5-hydroxytryptamine agonist (i.e., naratriptan, rizatriptan, zolmitriptan) in the previous 24 hours
  • have taken ergotamine-containing or ergot-type medications (such as dihydroergotamine, ergotamine, or methysergide) in the previous 24 hours


 

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