Brand Name
Allegra-D
Common Name
fexofenadine - pseudoephedrine
In this drug factsheet:
DIN (Drug Identification Number)How does this medication work? What will it do for me?
This combination medication contains two active ingredients:
- Pseudoephedrine belongs to a group of medications called decongestants.
Pseudoephedrine works by clearing and draining the nasal passages and sinuses.
- Fexofenadine belongs to a group of medications called antihistamines.
During an allergic reaction, the body produces a chemical called histamine,
which causes allergy symptoms. Fexofenadine works by blocking the action of
histamine in the body to reduce allergy symptoms.
Together, fexofenadine and pseudoephedrine work to relieve the symptoms
associated with allergic rhinitis, including nasal and sinus congestion,
sneezing, runny nose, itchy nose, and throat irritation, as well as red, itchy,
and watery eyes.
Your doctor may have suggested this medication for conditions other than the
ones listed in these drug information articles. If you have not discussed this
with your doctor or are not sure why you are taking this medication, speak to
your doctor. Do not stop taking this medication without consulting your doctor.
How should I use this medication?
Adults and children 12 years of age and older: The usual dose is one
caplet twice daily. People with poor kidney function may be prescribed a
lower dose by their doctor (i.e., one caplet once daily). Take this medication
on an empty stomach. Do not take this medication within 2 hours of taking an
antacid that contains aluminum or magnesium.
Many things can affect the dose of medication that a person needs, such as
body weight, other medical conditions, and other medications. If your doctor
has recommended a dose different from the ones listed here, do not change
the way that you are taking the medication without consulting your doctor.
It is very important to use this medication exactly as recommended by your
doctor. Do not use higher doses than those recommended by your doctor.
If you are using this medication regularly and you miss a dose, use it as soon
as possible. If it is almost time for your next dose, skip the missed dose and
carry on with your regular schedule. Do not take a double dose to make up for
a missed one.
Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.

What form(s) does this medication come in?
Each caplet engraved with "06/012D" on the white layer contains
fexofenadine HCl 60 mg and pseudoephedrine HCl 120 mg. Available as a bi-layer
clear film coated caplet (capsule-shaped tablet) with one half (lengthwise)
white to off-white and the other half tan. The fexofenadine layer is an immediate-release
formulation; the pseudoephedrine layer is a sustained-release formulation. Nonmedicinal ingredients: carnauba wax, cornstarch, croscarmellose sodium, hydroxypropyl
methylcellulose, magnesium stearate, microcrystalline cellulose, polyethylene
glycol, silicon dioxide and stearic acid.
Some medications may have other generic brands available. Always ask your doctor or pharmacist about the safety of switching between brands of the same medication.
Who should NOT take this medication?
This medication should not be used by anyone who:
- has taken monoamine oxidase (MAO) inhibitors within 14 days or who intends
to take such a medication during that time frame
- has narrow-angle glaucoma, urinary retention, severe high blood pressure,
or severe coronary artery disease
- is allergic to fexofenadine, pseudoephedrine, or any of the ingredients
of the medication
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