Brand Name
Atacand Plus
Common Name
candesartan - hydrochlorothiazide
In this drug factsheet:
DIN (Drug Identification Number)How does this medication work? What will it do for me?
Candesartan belongs to a family of medications known as angiotensin II receptor
blockers. Hydrochlorothiazide belongs to a family of medications known as
diuretics (or "water pills"). This combination medication
is used to lower high blood pressure. Candesartan works by relaxing blood
vessels. Angiotensin II is a chemical that the body releases to cause the constriction
(tightening up) of blood vessels. Candesartan blocks the action of angiotensin
II, resulting in the relaxation of the blood vessels. This relaxation causes
the blood pressure to decrease. Hydrochlorothiazide works by causing the body
to get rid of excess salt and water. Treatment is started with each of the ingredients
separately (i.e., candesartan and hydrochlorothiazide). Once the best dose of
each individual ingredient is found, the combination medication may then be
used at the appropriate dose.
Your doctor may have suggested this medication for conditions other than the
ones listed in these drug information articles. If you have not discussed this
with your doctor or are not sure why you are taking this medication, speak to
your doctor. Do not stop taking this medication without consulting your doctor.
How should I use this medication?
The usual adult dose is one tablet to be taken once daily at approximately
the same time each day, with or without food. Do not remove this medication
from the blister package until just before you take it.
Many things can affect the dose of medication that a person needs, such as
body weight, other medical conditions, and other medications. If your doctor
has recommended a dose different from the ones listed here, do not change
the way that you are taking the medication without consulting your doctor.
If you forget to take a dose, but remember within 12 hours, take it as soon
as possible and then go back to your regular dose. If more than 12 hours have
passed since your usual dose, skip that dose and carry on as usual with your
next dose. Never double-up on doses.
To ensure you receive the maximum benefit from the medication, it is important
to take this medication regularly and to follow your doctor's instructions regarding
blood pressure monitoring.
Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.

What form(s) does this medication come in?
Each oval, biconvex, peach tablet, with a score and marked "A" over "CS" on one side, contains candesartan cilexetil 16 mg and hydrochlorothiazide 12.5 mg. Nonmedicinal ingredients: calcium carboxymethylcellulose, hydroxylpropyl cellulose, iron oxide, lactose, magnesium stearate, maize starch, and polyethylene glycol.
Some medications may have other generic brands available. Always ask your doctor or pharmacist about the safety of switching between brands of the same medication.
Who should NOT take this medication?
This medication should not be taken by anyone who:
- is allergic to candesartan, hydrochlorothiazide, or any of the ingredients
of the product
- is allergic to sulfonamide-containing medications
- has severe kidney disease and cannot pass urine
- is pregnant
Did you find what you were looking for on our website? Please let us know.