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Drug Info > N > Norflex
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In this drug factsheet:

DIN (Drug Identification Number)


How does this medication work? What will it do for me?

Orphenadrine belongs to the group of medications called skeletal muscle relaxants. It is used to treat acute muscle spasms.

Muscle tightening or spasms result largely from signals in the nervous system telling the muscles to tighten or contract. Orphenadrine helps to relieve muscle tightening and stiffness by reducing the strength of those signals in the nervous system.

Muscle relaxants such as orphenadrine are used to help relieve the stiffness, pain, and discomfort caused by sprains and strains of the muscles in the neck, back, or other areas of the body. Your doctor may prescribe additional treatments such as appropriate rest, exercise, or physical therapy to help your stiff muscles.

Your doctor may have suggested this medication for conditions other than the ones listed in these drug information articles. As well, some forms of this medication may not be used for all of the conditions discussed here. If you have not discussed this with your doctor or are not sure why you are taking this medication, speak to your doctor. Do not stop taking this medication without consulting your doctor.

Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take this medication if their doctor has not prescribed it.

People who read this article also read about:

How should I use this medication?

The recommended adult dose of orphenadrine to be taken by mouth, is 100 mg twice daily, in the morning and evening. It may be taken with or without food. The recommended injectable dose is 60 mg injected into a vein or a muscle.

Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.

It is important to use this medication exactly as prescribed by your doctor. If you miss a dose, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.

Store this medication at room temperature. Protect it from heat and moisture. Protect the injectable from from light. Keep all forms of this medication out of the reach of children.

This medication is available under multiple brand names and/or in several different forms. Any specific brand name of this medication may not be available in all of the forms listed here. The forms available for the specific brand you have searched are listed under "What form(s) does this medication come in?"

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.

What form(s) does this medication come in?

Norflex is no longer being manufactured for sale in Canada. For brands that may still be available, search under orphenadrine. This article is being kept available for reference purposes only. If you are using this medication, speak with your doctor or pharmacist for information about your treatment options.

Who should NOT take this medication?

Do not take orphenadrine if you:

  • are allergic to orphenadrine or any ingredients of the medication
  • are experiencing cardiospasm
  • have an enlarged prostate
  • have bladder neck obstruction
  • have glaucoma
  • have myasthenia gravis
  • have pyloric or duodenal obstruction (blockage in the upper digestive system)
  • have stenosing peptic ulcers



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