In this drug factsheet:
What side effects are possible with this medication?
Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent. The side effects listed below are not experienced by everyone who takes this medication. If you are concerned about side effects, discuss the risks and benefits of this medication with your doctor.
The following side effects have been reported by at least 1% of people taking this medication. Many of these side effects can be managed, and some may go away on their own over time.
Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.
- abdominal pain
Although most of these side effects listed below don't happen very often, they could lead to serious problems if you do not check with your doctor or seek medical attention.
Check with your doctor as soon as possible if any of the following side effects occur:
- depression or mental confusion
- dizziness or lightheadedness
- headaches or stiff neck
- hearing problems
- pain while urinating or difficulty urinating
- swelling of feet or lower legs, or unexplained weight gain
- signs of liver damage (e.g., yellow skin or eyes, abdominal pain, dark urine, clay-coloured stools, loss of appetite, nausea and vomiting, or itching)
- vomiting or persistent nausea, indigestion, stomach pain, or diarrhea
Stop taking the medication and seek immediate medical attention if any of the following occur:
- bloody or black, tarry stools or dark urine
- bloody vomit with material that looks like coffee grounds
- blurred vision or other vision changes
- changes in the amount or colour of urine (such as red or brown urine)
- puffiness or swelling around the eyes, lips, or tongue
- severe stomach pain
- shortness of breath
- skin rash, hives or swelling, itching, chills, fever, muscle aches and pains, or other flu-like symptoms
- tightness in chest
- wheezing or difficulty breathing
Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking this medication.
Are there any other precautions or warnings for this medication?
Before you begin using a medication, be sure to inform your doctor of any medical conditions or allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use this medication.
Alcohol: People taking this medication should not drink alcohol as this can increase the risk of stomach problems with the medication.
Drowsiness/reduced alertness: Meloxicam may reduce mental or physical abilities required for performance of hazardous tasks such as operating machinery or driving a motor vehicle. Do not undertake such activities until you have determined that it does not have this effect on you.
Fertility: Fertility may be decreased in people taking this medication. This medication is not recommended for women who are trying to get pregnant.
Heart attack and stroke: The use of COX-2 NSAIDs, including meloxicam, is associated with an increased risk of heart attack and stroke. The risk is increased with higher total daily doses and taking the medication over long periods of time. If you have a history of heart disease, including heart attack and stroke, discuss with your doctor the benefits and risks of taking this medication. Ask your doctor about all available treatment options that may be right for you.
Informing health professionals: Be sure to tell any health professionals (including your doctor, nurse, pharmacist, and dentist) involved in your care that you are taking this medication, particularly if you are scheduled for heart surgery.
Medical conditions: If you have high blood pressure, heart failure, high cholesterol, diabetes, heart disease, kidney disease, or liver disease, or if you have had a stomach ulcer or bleeding in the past, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
Pregnancy: This medication is not recommended for pregnant women. If you become pregnant while taking this medication, contact your doctor immediately.
Breast-feeding: This medication is not recommended for breast-feeding women.
Children: The safety and effectiveness of using this medication have not been established for children.
Seniors: Seniors may have a higher risk of side effects and should be closely monitored by their doctors while taking this medication.
What other drugs could interact with this medication?
There may be an interaction between meloxicam and any of the following:
- angiotensin converting enzyme (ACE) inhibitors (e.g., ramipril, enalapril, captopril, quinapril)
- antiplatelet medications (e.g., acetylsalicylic acid, clopidogrel, and ticlopidine)
- glucocorticoid medications (e.g., cortisone, dexamethasone, prednisone)
- other NSAIDs (e.g., ibuprofen, naproxen)
- selective serotonin reuptake inhibitors (e.g., citalopram, fluoxetine, paroxetine)
If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:
- stop taking one of the medications,
- change one of the medications to another,
- change how you are taking one or both of the medications, or
- leave everything as is.
An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.
Medications other than those listed above may interact with this medication. Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.