insulin lispro mix
In this drug factsheet:DIN (Drug Identification Number)
|02240294 ||HUMALOG MIX 25 CARTRIDGE/KWIKPEN|
|02240295 ||HUMALOG MIX 25 PEN|
How does this medication work? What will it do for me?
Insulin is a naturally occurring hormone made by the pancreas that helps our body use or store blood glucose (sugar) it gets from food. For people with diabetes, either the pancreas does not make enough insulin to meet the body's requirements, or the body cannot properly use the insulin that is made. As a result, glucose cannot be used or stored properly and accumulates in the bloodstream. Insulin injected under the skin helps to lower blood glucose levels.
There are many different types of insulin that are absorbed at different rates and work for varying periods of time. This type of premixed insulin contains a mixture of fast-acting and intermediate-acting insulins. Insulin lispro mix contains insulin lispro and insulin lispro protamine suspension. Insulin lispro is a rapid-acting insulin. Insulin lispro protamine suspension is absorbed more slowly than insulin lispro, lowering the blood glucose levels over a prolonged period of time.
Insulin lispro is used by people with diabetes who have their blood glucose under control and have found a particular ratio of fast-acting to intermediate-acting insulin that works best for them. Insulin lispro mix starts working 10 to 15 minutes after injection, has its maximum effect between 1 and 8 hours, and stops working after about 18 hours.
Your doctor may have suggested this medication for conditions other than those listed in these drug information articles. As well, some forms of this medication may not be used for all of the conditions discussed here. If you have not discussed this with your doctor or are not sure why you are using this medication, speak to your doctor. Do not stop using this medication without consulting your doctor.
Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to use this medication if their doctor has not prescribed it.
People who read this article also read about:
How should I use this medication?
Your required dose of insulin depends on how much natural insulin your pancreas is producing and how well your body is able to use the insulin. Your doctor or diabetes educator will determine the appropriate dose for you according to various lifestyle factors and the blood glucose values obtained while monitoring your blood glucose.
Your dose of insulin should be injected subcutaneously (under the skin) exactly as instructed by your doctor or diabetes educator. Do not inject insulin lispro into the vein and do not use insulin lispro mix in insulin infusion pumps. The dose of insulin is measured in international units (IU). Each 1 mL of insulin contains 100 IU. Insulin lispro mix is injected under the skin within 15 minutes before the start of a meal. There are many variations of insulin dosing.
Mix premixed insulin by slowly rolling the bottle or pen between your hands. Premixed insulin suspension should appear cloudy and white. Do not use the insulin if it looks lumpy or grainy, seems unusually thick, sticks to the bottle or vial, or appears discoloured. Do not use it if it contains crystals, if the bottle or vial looks frosted, or if the suspension remains clear after being rolled between your hands.
Many things can affect the dose of a medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are using the medication without consulting your doctor.
It is very important that you use this medication exactly as prescribed by your doctor. The timing of insulin with respect to your meals is crucial to keeping blood glucose under control and preventing unwanted side effects. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.
Keep unopened bottles of insulin in the refrigerator until needed. They may be used until the expiry date on the label. Never allow insulin to freeze. Insulin that is currently in use may be kept at room temperature for no more than 28 days and then discarded. Insulin must not be exposed to extremely hot temperatures or to sunlight. Keep insulin out of reach of children.
Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.
What form(s) does this medication come in?
Humalog Mix25 Cartridge/Kwikpen
Every 1 mL contains 100 units of human insulin analogue (insulin lispro mix; 25% insulin lispro and 75% insulin lispro protamine suspension). Nonmedicinal ingredients: dibasic sodium phosphate, glycerin, liquefied phenol, m-Cresol distilled, protamine sulfate, water for injection, and zinc oxide. Hydrochloride acid and/or sodium hydroxide may be added to adjust pH.
Who should NOT take this medication?
Insulin lispro mix should not be used by anyone who:
- is allergic to insulin or to any of the ingredients of the medication
- has low blood glucose (hypoglycemia)