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Drug Info > C > Chlorax
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Brand Name

Common Name
chlordiazepoxide - clidinium

In this drug factsheet:

What side effects are possible with this medication?

Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent. The side effects listed below are not experienced by everyone who takes this medication. If you are concerned about side effects, discuss the risks and benefits of this medication with your doctor.

The following side effects have been reported by at least 1% of people taking this medication. Many of these side effects can be managed, and some may go away on their own over time.

Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.

  • bloated feeling
  • decreased sweating
  • dizziness
  • drowsiness
  • dry mouth
  • headache

Although most of these side effects listed below don't happen very often, they could lead to serious problems if you do not check with your doctor or seek medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

  • constipation
  • eye pain
  • insomnia
  • mental depression
  • nervousness or irritability
  • shortness of breath
  • skin rash or hives
  • slow heartbeat
  • sore throat and fever
  • unusual excitement
  • yellow eyes or skin

Stop taking the medication and seek immediate medical attention if any of the following occur:

  • confusion
  • difficult urination
  • drowsiness (severe)
  • dryness of nose, mouth, throat (severe)
  • fast heartbeat
  • unusual warmth, dryness, and flushing of skin

Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking this medication.

Are there any other precautions or warnings for this medication?

Before you begin using a medication, be sure to inform your doctor of any medical conditions or allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use this medication.

Dental problems: Since one of the ingredients may cause a dry mouth, there is an increase risk of dental disease.

Dependence and withdrawal: Physical dependence (a need to take regular doses to prevent physical symptoms) has been associated with benzodiazepines such as chlordiazepoxide - clidinium. Severe withdrawal may occur if the dose is significantly reduced or suddenly discontinued. These symptoms include seizures, irritability, nervousness, sleep problems, agitation, tremors, diarrhea, abdominal cramps, vomiting, memory impairment, headache, muscle pain, extreme anxiety, tension, restlessness, and confusion. Reducing the dose gradually under medical supervision can help prevent or decrease these withdrawal symptoms.

Drowsiness/reduced alertness: Because chlordiazepoxide - clidinium may cause drowsiness and sedation, do not engage in activities that require mental alertness, judgment, and physical coordination (such as driving or operating machinery) while taking this medication. This is particularly true when first starting the medication and until you have established that chlordiazepoxide - clidinium does not affect you this way. Alcohol ingestion can increase the drowsiness effects and should be avoided.

Medical conditions: Tell your doctor if you have any of the following conditions, as it may influence whether your doctor recommends this medication:

  • chronic obstructive pulmonary disease (COPD)
  • depression
  • glaucoma (open-angle)
  • hiatus hernia
  • high blood pressure
  • intestinal blockage
  • kidney disease
  • liver disease
  • mental illness
  • myasthenia gravis
  • overactive thyroid
  • ulcerative colitis
  • xerostomia (condition with severe loss of saliva)

People with an addiction to alcohol or other medications should not take chlordiazepoxide, except in rare situations under medical supervision.

Pregnancy: This medication should not be used during pregnancy unless the benefits outweigh the risks.

Breast-feeding: This medication may pass into breast milk. If you are a breast-feeding mother and are taking chlordiazepoxide - clidinium, it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.

Children: The safety and effectiveness of using this medication have not been established for children.

Seniors: Seniors may be at increased risk for the sedative and impaired coordination effects of this medication. They need to use extra caution, for example, when getting up during the night.

What other drugs could interact with this medication?

There may be an interaction between chlordiazepoxide - clidinium and any of the following:

  • alcohol
  • antacids
  • anticholinergic medications (e.g., atropine, hyoscyamine)
  • clarithromycin
  • diarrhea medicines that contain kaolin or attapulgite
  • fluconazole
  • fluvoxamine
  • itraconazole
  • ketoconazole
  • medications that cause sedation (e.g., antidepressants, benzodiazepines, barbiturates, MAO inhibitors, narcotics, phenothiazines, antihistamines)
  • nefazodone
  • phenytoin
  • potassium chloride
  • theophylline
  • warfarin

If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:

  • stop taking one of the medications,
  • change one of the medications to another,
  • change how you are taking one or both of the medications, or
  • leave everything as is.

An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.

Medications other than those listed above may interact with this medication. Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.



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