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High Blood Pressure > Related Conditions > Mitral Valve Prolapse
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Mitral Valve Prolapse

(MVP · Heart Murmur)

In this condition factsheet:

The Facts on Mitral Valve Prolapse

Mitral valve prolapse (MVP) is a common condition that affects one of the heart's valves. It occurs in about 1 out of every 50 people and is seen twice as often in women than in men. This condition can be undetected for years and doesn't usually cause serious heart problems. Most people with MVP require no treatment.

Causes of Mitral Valve Prolapse

The mitral valve is the heart valve located between the upper and lower chambers of the left side of the heart. The mitral valve is made up of two flaps and controls the blood flow from the top chamber of the left side of the heart (the left atrium) to its bottom chamber (the left ventricle).

But in MVP, one or both of the flaps are too big. The valve can't close properly and will bulge out or prolapse into the left atrium. With a stethoscope, doctors may hear the soft "clicking" sound of the bulging. Sometimes, the bulging creates a little space between the flaps, which lets the blood leak backwards into the left atrium from the ventricle. This leak can cause a "whooshing" sound that can also be heard with the stethoscope.

MVP is sometimes inherited. Some people with MVP have minor deformities of the chest, back, and spine. In rare cases, inherited diseases such as Marfan's syndrome have been associated with MVP.

Symptoms and Complications of Mitral Valve Prolapse

MVP symptoms are usually minor. If you have MVP, you may feel perfectly fine or may not even know about it. Most people with MVP have no symptoms. Some of the symptoms people feel are often puzzling, since they aren't directly caused by the valve malfunction.

The symptoms of MVP include:

  • irregular heartbeat or palpitations
  • tachycardia, or increased heartbeats and pounding in the chest, often occurring after exercise
  • chest pain that can last from seconds to hours, often when you are resting
  • panic attacks such as a sudden feeling of anxiety or doom
  • fatigue, dizziness, and weakness, sometimes misdiagnosed as chronic fatigue syndrome
  • blood pressure that falls below normal when you stand up, causing lightheadedness

Very few people with MVP experience complications. In rare cases, complications of MVP include:

  • irregular heartbeat (arrhythmia) and chest pain (angina pectoris) - both of these conditions may be treated with medications such as beta-blockers
  • blood clots that form directly on the mitral valve and increase the risk of stroke
  • endocarditis, the most serious MVP-related problem.

Endocarditis is a bacterial infection of the mitral valve, which can be treated with antibiotics. People with MVP sometimes develop endocarditis after having certain dental or surgical procedures that increase the risk of introducing bacteria into the blood.



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