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Multiple Sclerosis > Related Conditions > Chronic Pain
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Chronic Pain

(Pain · Long-term pain)


In this condition factsheet:


The Facts on Chronic Pain

Everyone has experienced pain at some time or other. A cut, a sports injury, childbirth, surgery, or kidney stones all can produce varying degrees of pain. In these cases, the pain has a known cause and resolves when the cause is no longer there. This type of pain is acute pain. Acute pain performs a function - it warns the body of a problem or injury.

Chronic pain, which is pain lasting months or years, is much different. The pain itself rarely continues to perform a useful function. Chronic pain can be quite disabling, often preventing people from working and enjoying life. It can lead to people feeling isolated, angry, frustrated, and guilty.

Certain portions of this content are made possible by Novartis.

Causes of Chronic Pain

Many medical conditions or injuries can cause chronic pain. Some people will continue to experience pain long after recovering from an initial injury, such as a back injury. Other chronic pain is caused by chronic diseases such as arthritis or cancer. Some people have pain that does not have an identifiable cause. This is not to say that the pain is not real. Whatever the cause, chronic pain is real and should be treated.

The following conditions may be associated with chronic pain:

  • cancer
  • fibromyalgia
  • spinal injury
  • headaches
  • back injury
  • arthritis
  • nerve inflammation or damage

Sometimes pain can be felt in a part of the body that is no longer there. This is called phantom limb pain, which develops as a result of amputation. When pain in one part of the body is felt in another part of the body, it is called referred pain.

The internal organs are not very responsive to pain; instead, pain in these areas may be felt more as a diffuse pain (i.e., pain spread over a large area), which is not easy to localize.

Acute pain results when a disease or injury sends a signal to special sensory nerve endings called nociceptors. Nociceptors are located in the skin, as well as in other structures including blood vessels and tendons. Pain signals travel from the nociceptors, through the sensory nerves, and up the spinal cord to the thalamus in the brain. The signal is then sent to the cerebral cortex, the part of the brain that processes thought.

On the way to the brain, natural body chemicals can change the pain signal. Substance P makes the pain signal stronger. Endorphins make it weaker. Pain is not actually felt until the message or signals get to the brain. Chronic pain can originate at many points in the above pathway.

The cerebral cortex and the limbic system, which are the brain areas controlling emotion, process pain signals. How much pain is felt depends on a number of factors. Factors that increase how badly pain is felt include the following:

  • previous bad experiences with pain
  • insomnia
  • anxiety
  • depression

Anxiety can make pain much worse. Not knowing the cause of pain makes people anxious. The pain often seems less severe once they have a diagnosis of their medical condition. Worry about the seriousness of their condition can often also increase the severity of the pain.

Symptoms and Complications of Chronic Pain

Living with chronic pain can create a vicious cycle of anxiety, dependence on other people, and sleep deprivation. Chronic long-term pain can make it unpleasant for people to live their daily life normally and it saps their energy.

People suffering from chronic pain might stop social activities because of the pain. They might feel dependent on other people to help with daily tasks such as shopping. It can be hard to sleep for someone who is in pain, or worried about being in pain. Constant sleep deprivation can lead to depression. Feeling helpless because of chronic pain can also make people feel worthless and demoralized.



 

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